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Cancer Currents for May 2014

Mark Israel

If it's not measurable it probably doesn't exist.

Every five years an important measure of our contribution to the national commitment to prevent and cure cancer is the renewal of our cancer center support grant from the National Cancer Institute. The first step in the renewal process was the submission of our 1,600+ page proposal for the next five years, as well as a summary of what we’ve been up to.

The second step occurs on June 12, when more than 20 nationally acclaimed cancer investigators will come to Dartmouth to evaluate the quality of our cancer research enterprise. To date the response of our NCCC members has been remarkably strong and generous, which has been amazingly gratifying. In the coming weeks I will be asking for an even greater commitment as we prepare for the arrival of the NCI review team.

Our goal is to assure funding for our research enterprise, basic science, translational investigations, population-based studies, and clinical trials. These all occur in the setting of collaborative expertise, ready access to advanced technologies, and an environment in which scholarship is supported and appreciated.

Our NCI support grant seeks to secure key aspects of the infrastructure that promotes outstanding science at Dartmouth. Your continuing assistance in assuring the success of our grant is deeply appreciated.

Mark Israel, Director

Core Grant Site Visit Update

Preparing for the upcoming NCI support grant site visit on Thursday, June 12, 2014 is a top priority for everyone at NCCC. Please mark your calendars with these important dates:

Presentations: The site visit includes a review of our internal scientific protocol review process, and the site visitors have selected five recent Dartmouth-initiated studies to assess. We will have external "mock" site visitors coming in May to review the Shared Resource (Wednesday, May 7) and Program (Wednesday, May 14) presentations. These presentations will emphasize scientific vignettes that illustrate the quality of our research and the contribution of the Cancer Center to that work. Final all-day rehearsals are scheduled for Tuesday, May 20th and Wednesday, May 28th. NCCC Members are encouraged to attend the June 12th presentations of their program leaders, to convey to the site visitors the center-wide engagement with the work being reported.
All staff site visit practice days: Wednesday, May 14th, Tuesday, May 20th, and Wednesday, May 28th.

Celebrating Our Doctors and Volunteers

We had a lot of fun saying thank you to the doctors and volunteers of Norris Cotton Cancer Center last month.

Though National Doctors' Day 2014 officially took place on Sunday, March 30, physicians from the Lymphoma Tumor Board at Norris Cotton Cancer Center were treated to a special musical gift from the Dartmouth Rockapellas on the following Tuesday.

 

We also enlisted the talent of some of our directors and staff members to commemorate National Volunteer Week 2014. They got together, and got down, to say a special "Thank You!" to the many who dedicate their time to supporting our patients and services.

New Molecular Tumor Board

The NCCC Molecular Tumor Board, under the jurisdiction of the Early Phase Trials Clinical Oncology Group (EPT COG), held its first meeting on November 20, 2013. This group of NCCC/ DHMC medical and surgical oncologists, hematologists, molecular pathologists, molecular scientists, geneticists, ethicists, genetic counselors, and social workers meets to provide clinical interpretation of molecular test results and clinical trial recommendations in the format of a scientific, multi-disciplinary discussion. The director is Mary Chamberlin, MD, and the co-director is Todd Miller, PhD.

Molecular profiling has become an integral component in the management of patients with several types of malignancies including non-small cell lung cancer, colorectal cancer, and melanoma. As clinicians it is our responsibility to analyze the evidence behind the use of any drug or trial, the risks it may present to our patients, and the suitability of our patients for these trials. This tumor board provides clinicians and scientists who understand molecular pathways a venue to meet regularly to discuss these results in order to provide the best recommendations for our patients.

The Molecular Tumor Board is the first of its kind at DHMC, with discussions of cancers of any type with molecular scientists and geneticists as regular attendees. The formation of this tumor board coincides nicely with at least two other pioneering efforts at Dartmouth-Hitchcock soon to be up and running: the development of tissue banks from patients who volunteer to allow their tumor tissue to be anonymously stored and analyzed—the Tumor Tissue Molecular Mapping or T2M2 Trial with Dr. Chris Amos as the principle investigator, and a clinical treatment trial for any tumor type (D13214) that will track how effective targeted therapy to the tumor molecular footprint is with Drs. Chamberlin and Miller as co-principle investigators. For more information please email Dr. Chamberlin at Mary.D.Chamberlin@hitchcock.org

Onega Receives Herbert. M. Stauffer Award

Tracy Onega Tracy L. Onega, PhD, associate professor of Community and Family Medicine and of the Dartmouth Institute, Geisel School of Medicine at Dartmouth

Tracy L. Onega, PhD, associate professor of Community and Family Medicine and of the Dartmouth Institute, Geisel School of Medicine at Dartmouth, and researcher at Norris Cotton Cancer Center has won the Herbert M. Stauffer Award for Best Clinical Paper in Academic Radiology in 2013. Her study, "Establishment of a gold standard for test sets: variation in interpretive agreement of expert mammographers," was published in the June 2013 issue of Academic Radiology. The Stauffer Award commemorates the work of Dr. Herbert M. Stauffer, who established the Radiology-Physiology Laboratory at Temple University in Philadelphia. All papers that were published in Academic Radiology during 2013 were eligible. The award was presented at the 62nd Annual Meeting of the Association of University Radiologists in Baltimore, Maryland, April 1-4, 2014.

New Staff

Stephanie Cameron has joined NCCC as Oncology Programs coordinator. She most recently worked on the inpatient hematology/oncology floor of DHMC, and is currently pursuing a master's degree in public health.

Hannah Paul has joined The Prouty team as temporary volunteer coordinator. She most recently worked as a recruiter with Technical Needs in Lebanon.

Julie Schettino joined the Office of Clinical Research as a clinical research administrator and will be working with the Hematology Group. She was previously an intelligence analyst with Six3 Systems.

Arin Chiasson joined the Office of Clinical Research as a clinical research administrator. She will be working the Breast Team, and comes to us from Olympus Biotech.

Nurture Yourself Workshop for Oncology Staff May 17

NCCC's first renewal workshop for staff in March was enthusiastically received by 18 participants. Now is your chance to try a learning and experiential activity that is refreshing and inspiring on Saturday, May 17, from 9 a.m. to 12:30 p.m., in Auditoria C and D, DHMC.

This workshop will incorporate the arts to nurture and renew anyone who works with oncology patients in any capacity—from scheduling, social work through clinical care. You will be led through a morning of safe, mind-refreshing activities led by Marv Klassen-Landis, Rebecca Gottesman, Margaret Stephens, and Deb Steele. Absolutely no experience is necessary or required in any of the activities. The fee is $10 and includes breakfast and lunch. Space is limited, so please sign up early. Three contact hours will be given to nurses who attend.

To register, please visit: http://med.dartmouth-hitchcock.org/ccehs.html Additional information is included on this flyer. If you have questions or want to talk to a nurse or other staff who took the March workshop please contact Deb Steele at 603-650-7751 or Deborah.J.Steele@hitchcock.org (for questions about registration email ccehs@hitchcock.org).

Dartmouth Secure Wireless Network is now in Some DHMC Areas

The Dartmouth Secure wireless network was recently introduced into some areas of DHMC (Rubin, Borwell, and Matthews-Fuller library), so if you have to access applications or resources that require the VPN, you can use Dartmouth Secure instead.
To connect, open the list of available wireless networks and select Dartmouth Secure. Enter Username (KIEWIT\your NetID) and password (your Dartmouth.edu password)

Two important things to note:

  • Dartmouth Secure is different from DHMC Secure. If you connect to Dartmouth Secure, you won't be able to access NCCC resources like the P: and S: drives, as well as printers.
  • Dartmouth Secure is a completely wireless network. If you access the internet from a desktop computer that doesn't have wireless capabilities, you won't be able to use Dartmouth Secure.

If you have questions about Dartmouth Secure or experience any problems connecting, please send us a message at csnccc@dartmouth.edu.

Friends News

Raise Money for NCCC at the TI Disco Fever Race

On Saturday, May 17, 2014, get your disco shoes on and run a 5K or 10K to benefit Dartmouth-Hitchcock Norris Cotton Cancer Center. This groovy run begins and ends at the World Sports Grille, Manchester, NH. You will boogey down our USTF certified 5k / 10k routes through the historic mills, onto a paved foot trail all while Disco music is playing along the course.

After you've worked up a sweat, cool off at the post-race disco party! The festivities will offer live music, food, raffles, and awards for the overall male and female winners in each category, and prizes for the best male and female Disco outfits! For more information, please visit the race website at www.totalimagept.com.

Kicking it off in style!

Get in The Prouty spirit by attending a Kick-off party! Bring a friend to our Hanover Inn celebration on Thursday, May 8, 5:30-7 p.m. and eat, drink, celebrate and learn how we're advancing the fight against cancer. Live in the Sunapee area? Attend our newest celebration on Saturday, May 10, at the Lake Sunapee Protective Association, 63 Main St., Sunapee, 5:30-7pm. rsvp to mgeliassen@comcast.net

Announcements and Events:
  • Tip Top Café Cork and Canvas Class
    Welcome one and all to the first D-H and Dartmouth College Tip Top Pottery Cork and Canvas class! Join other D-H and College employees on Wednesday, May 14, from 5:30-8:30 p.m., for a fun evening with an easy to follow project that you will be delighted to hang on your wall or gift to someone! Bring your favorite beverage (they supply the wine glasses) and dinner. Food from Tip Top Café (which is right next door) is also available. Cost is only $40 for all supplies and instructions. To sign up, go to http://www.tiptoppottery.com/cork-and-canvas.html and choose the Cork and Canvas link. Email tiptoppottery@gmail.com if you have any questions. (Tip Top Pottery is located at 85 North Main Street, White River Junction, VT.  This will be a very popular class so make sure to sign up early!)

Check out VOX for more listings on classes and events around the Dartmouth College Campus

  • Weight Watchers Open House at DHMC
    Learn about DHMC Weight Watchers at work at an open house on Thursday, May 8, 2014, noon to 12:45 p.m., Level 5 Fitness Space, DHMC, Faulkner Building. Weight Watchers @ Work meets weekly at DHMC on Thursdays, 12-12:45 p.m. Registration is required and the fee is$39.95/month for a monthly pass (prepays a month at a time and automatically renews). You can register and purchase your monthly pass online before coming to the meeting (but you can come to the first one without registering). To register for employee access go to wellness.weightwatchers.com: Company ID: 21247; Company Pass code: WW21247

More information announcements and events at the Dartmouth Medical Center

  • Dartmouth Ranked Among the Top 25 Medical School Libraries
    Congrats to the Biomedical Libraries at Dartmouth, which were recently included in a list of the world's "25 Most Impressive University Medical School Libraries." Read more

More information on announcements and events at the Geisel School of Medicine at Dartmouth

NCCC in the Media: April, 2014


 "Dartmouth doctors, engineers find breast cancer surgery breakthrough" (Richard Barth) Union Leader, 3/31/14; Vermont Digger
"
What Doctors Tell Their Friends About Preventing Cancer" (Dr. Gerald Gehr) Redbook, March 2014.
"Dartmouth researchers studying new pancreatic cancer treatment" (Brian Pogue) Union Leader, 4.2.14; Science Codex,
"Certain Genetic Variants May Help Identify Patients at Increased Risk of Bladder Cancer Recurrence" (Angeline Andrew) Health Canal, 4/2/14, Science Codex,
"Watch: Kids Confuse Apple Slices for French Fries in Fast Food Ads" (James Sargent)
Time
, 4/1/14; WBUR,  Medical Xpress, Medical News Today,Parents Magazine
"Study by NH researchers could produce advances in breast cancer treatment"  (Tsongalis) Union Leader, 4/3/14
"Dartmouth Creates GPS-Like System to Detect Breast Cancer," (Richard Barth) HealthData Management, 4.4.14
"Tobacco marketing reaches 1 in 10 teens and 1 in 4 young adults," (Samir Soneji) Business Standard, 4/7/14
"
Disruption of VISTA Plays an Important role in Regulating Immune Response" (Wang/Noelle)  Health Canal,4/8/14
"
Magnetic nanoparticle (mNP) hyperthermia in breast cancer treatment," (.P. Jack Hoopes)
NewsMedical
, 4/8/14
"
Why listening to rap music drives teenagers to drink: Study finds they want the same alcohol brands as their their idols,"  (James Sargent,) Daily Mail, 4/9/14
"Researchers identify potential therapeutic target for deadly brain cancer," (Michael Spinella) Medical XPress, 4/8/14; Health Canal; Bio-Medicine
"Dosage and schedules may improve effects of PI3K-inhibitors to target breast cancer tumors," News Medical, 4/10/14
"Study: Music Is Just Advertisement for Alcohol Brands," (James Sargent) 4/10/14, The Atlantic; Parents Magazine;

Dates to note

May 19, 2014
Immunology Symposium
8:00 a.m. to 3:30 p.m.
DHMC Lebanon

May 30-June 3, 20114
ASCO 50th Annual Meeting
Chicago, Illinois

Grand Rounds

Norris Cotton Cancer Center typically holds Grand Rounds lectures on Tuesdays from 12 to 1 p.m. in the Barbara E. Rubin Building at Dartmouth-Hitchcock Medical Center. Our Events for Cancer Professionals listing shows our upcoming lectures. Most lectures can also be viewed live online. In addition, you can view recorded webcasts, or listen to recorded podcasts.