Recent Publications

Andrew AS, Hu T, Gu J, Gui J, Ye Y, Marsit CJ, Kelsey KT, Schned AR, Tanyos SA, Pendleton EM, Mason RA, Morlock EV, Zens MS, Li Z, Moore JH, Wu X, Karagas MR (2012). HSD3B and gene-gene interactions in a pathway-based analysis of genetic susceptibility to bladder cancer. PloS one 7(12):e51301. 3526593: PMC3526593 Link

Balboni AL, Hutchinson JA, Decastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, Direnzo J (2013). DeltaNp63alpha-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer research 73(2):1020-1030. PMC Link

Balboni AL, Hutchinson JA, Decastro AJ, Cherukuri P, Liby K, Sporn MB, Schwartz GN, Wells WA, Sempere LF, Yu PB, Direnzo J (2013, In press). DeltaNp63alpha-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells. Cancer Res [Epub ahead of print]. PMC Link

Biswal BK, Beyrouthy MJ, Hever-Jardine MP, Armstrong D, Tomlinson CR, Christensen BC, Marsit CJ, Spinella MJ (2012). Acute hypersensitivity of pluripotent testicular cancer-derived embryonal carcinoma to low-dose 5-Aza deoxycytidine is associated with global DNA damage-associated p53 activation, anti-pluripotency and DNA demethylation. PLoS One 7(12):e53003. 3531428: PMC3531428 Link

Bush WS, Moore JH (2012). Chapter 11: Genome-wide association studies. PLoS computational biology 8(12):e1002822. 3531285: PMC3531285 Link

Connor JP, Cristea MC, Lewis NL, Lewis LD, Komarnitsky PB, Mattiacci MR, Felder M, Stewart S, Harter J, Henslee-Downey J, Kramer D, Neugebauer R, Stupp R (2013). A phase 1b study of humanized KS-interleukin-2 (huKS-IL2) immunocytokine with cyclophosphamide in patients with EpCAM-positive advanced solid tumors. BMC Cancer 13(1):20. PMC Link

Coria A, Noel F, Bonhomme J, Rouzier V, Perodin C, Marcelin A, Li Z, Tosteson TD, Deschamps MM, Wright PF, Pape JW (2012). Consideration of postpartum management in HIV-positive Haitian women: An analysis of CD4 decline, mortality, and follow-up after delivery. J Acquir Immune Defic Syndr 61(5):636-643. PMC Link

Croteau W, Jenkins MH, Ye S, Mullins DW, Brinckerhoff CE (2013). Differential mechanisms of tumor progression in clones from a single heterogeneous human melanoma. J Cell Physiol 228(4):773-780.
PMC Link

Davidson BA, Vethanayagam RR, Grimm MJ, Mullan BA, Raghavendran K, Blackwell TS, Freeman ML, Ayyasamy V, Singh KK, Sporn MB, Itagaki K, Hauser CJ, Knight PR, Segal BH (2013, In press). NADPH oxidase and Nrf2 regulate gastric aspiration-induced inflammation and acute lung injury. J Immunol [Epub ahead of print]. PMC Link

Dorosko SM, Cherukuri P, Direnzo J (2012). Unanticipated reversal of polarity in primary human mammospheres cultured in ultra-low attachment plates. J Pharm Sci 101(12):4666-4668. PMC Link

Dowty JG, Win AK, Buchanan DD, Lindor NM, Macrae FA, Clendenning M, Antill YC, Thibodeau SN, Casey G, Gallinger S, Le Marchand L, Newcomb PA, Haile RW, Young GP, James PA, Giles GG, Gunawardena SR, Leggett BA, Gattas M, Boussioutas A, Ahnen DJ, Baron JA, Parry S, Goldblatt J, Young JP, Hopper JL, Jenkins MA (2012, In press). Cancer risks for MLH1 and MSH2 mutation carriers. Human mutation [Epub ahead of print]. PMC Link

Dulai PS, Pohl H, Levenick JM, Gordon SR, Mackenzie TA, Rothstein RI (2013, In press). Radiofrequency ablation for long- and ultralong-segment Barrett's esophagus: A comparative long-term follow-up study. Gastro Endo [Epub ahead of print]. PMC Link

Dumont LJ, Cancelas JA, Dumont DF, Siegel AH, Szczepiorkowski ZM, Rugg N, Pratt PG, Worsham DN, Hartman EL, Dunn SK, O'Leary M, Ransom JH, Michael RA, Macdonald VW (2013). A randomized controlled trial evaluating recovery and survival of 6% dimethyl sulfoxide-frozen autologous platelets in healthy volunteers. Transfusion 53(1):128-137. PMC Link

Fung E, Patsopoulos NA, Belknap SM, O'Rourke DJ, Robb JF, Anderson JL, Shworak NW, Moore JH (2012, In press). Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of Warfarin. Seminars in thrombosis and hemostasis [Epub ahead of print]. PMC Link

Geurink PP, van der Linden WA, Mirabella AC, Gallastegui N, de Bruin G, Blom AE, Voges MJ, Mock ED, Florea BI, van der Marel GA, Driessen C, van der Stelt M, Groll M, Overkleeft HS, Kisselev AF (2013, In press). Incorporation of non-natural amino acids improves cell permeability and potency of specific inhibitors of proteasome trypsin-like sites. J Med Chem [Epub ahead of print]. PMC Link

Ghosh M, Shen Z, Fahey JV, Crist SG, Patel M, Smith JM, Wira CR (2013). Pathogen recognition in the human female reproductive tract: Expression of intracellular cytosolic sensors NOD1, NOD2, RIG-1, and MDA5 and response to HIV-1 and neisseria gonorrhea. Am J Reprod Immunol 69(1):41-51. 3518676: PMC3518676 Link

Glaser AK, Davis SC, Voigt WH, Zhang R, Pogue BW, Gladstone DJ (2013). Projection imaging of photon beams using Cerenkov-excited fluorescence. Phys Med Biol 58(3):601-619. PMC Link

Goldman MB, Troisi R, Rexrode KM, Woman and Health. 2nd ed. 2012: Academic Press.
Harvey JA, Gard CC, Miglioretti DL, Yankaskas BC, Kerlikowske K, Buist DS, Geller BA, Onega TL (2012). For the Breast Cancer Surveillance C: Reported Mammographic Density: Film-Screen versus Digital Acquisition. Radiology. PMC Link

Hein R, Maranian M, Hopper JL, Kapuscinski MK, Southey MC, Park DJ, Schmidt MK, Broeks A, Hogervorst FB, Bueno-de-Mesquit HB, Muir KR, Lophatananon A, Rattanamongkongul S, Puttawibul P, Fasching PA, Hein A, Ekici AB, Beckmann MW, Fletcher O, Johnson N, Dos Santos Silva I, Peto J, Sawyer E, Tomlinson I, Kerin M, Miller N, Marmee F, Schneeweiss A, Sohn C, Burwinkel B, Guenel P, Cordina-Duverger E, Menegaux F, Truong T, Bojesen SE, Nordestgaard BG, Flyger H, Milne RL, Perez JI, Zamora MP, Benitez J, Anton-Culver H, Ziogas A, Bernstein L, Clarke CA, Brenner H, Muller H, Arndt V, Stegmaier C, Rahman N, Seal S, Turnbull C, Renwick A, Meindl A, Schott S, Bartram CR, Schmutzler RK, Brauch H, Hamann U, Ko YD, Wang-Gohrke S, Dork T, Schurmann P, Karstens JH, Hillemanns P, Nevanlinna H, Heikkinen T, Aittomaki K, Blomqvist C, Bogdanova NV, Zalutsky IV, Antonenkova NN, Bermisheva M, Prokovieva D, Farahtdinova A, Khusnutdinova E, Lindblom A, Margolin S, Mannermaa A, Kataja V, Kosma VM, Hartikainen J, Chen X, Beesley J, Investigators K, Lambrechts D, Zhao H, Neven P, Wildiers H, Nickels S, Flesch-Janys D, Radice P, Peterlongo P, Manoukian S, Barile M, Couch FJ, Olson JE, Wang X, Fredericksen Z, Giles GG, Baglietto L, McLean CA, Severi G, Offit K, Robson M, Gaudet MM, Vijai J, Alnaes GG, Kristensen V, Borresen-Dale AL, John EM, Miron A, Winqvist R, Pylkas K, Jukkola-Vuorinen A, Grip M, Andrulis IL, Knight JA, Glendon G, Mulligan AM, Figueroa JD, Garcia-Closas M, Lissowska J, Sherman ME, Hooning M, Martens JW, Seynaeve C, Collee M, Hall P, Humpreys K, Czene K, Liu J, Cox A, Brock IW, Cross SS, Reed MW, Ahmed S, Ghoussaini M, Pharoah PD, Kang D, Yoo KY, Noh DY, Jakubowska A, Jaworska K, Durda K, Zlowocka E, Sangrajrang S, Gaborieau V, Brennan P, McKay J, Shen CY, Yu JC, Hsu HM, Hou MF, Orr N, Schoemaker M, Ashworth A, Swerdlow A, Trentham-Dietz A, Newcomb PA, Titus L, Egan KM, Chenevix-Trench G, Antoniou AC, Humphreys MK, Morrison J, Chang-Claude J, Easton DF, Dunning AM (2012). Correction: Comparison of 6q25 breast cancer hits from Asian and European genome wide association studies in the Breast Cancer Association Consortium (BCAC). PloS one 7(10). 3525690: PMC3525690 Link

Henderson LM, Hubbard RA, Onega TL, Zhu W, Buist DS, Fishman P, Tosteson AN (2012). Assessing health care use and cost consequences of a new screening modality: The case of digital mammography. Med Care 50(12):1045-1052. PMC Link

Hickey DK, Fahey JV, Wira CR (2013). Estrogen receptor alpha antagonists mediate changes in CCL20 and CXCL1 secretions in the murine female reproductive tract. Am J Reprod Immunol 69(2):159-167. 3538084: PMC3538084 Link

Hoffman RM, Barry MJ, Roberts RG, Sox HC (2012). Reconciling primary care and specialist perspectives on prostate cancer screening. Ann Fam Med 10(6):568-571. 3495932: PMC3495932 Link

Hubbard RA, Zhu W, Onega TL, Fishman P, Henderson LM, Tosteson AN, Buist DS (2012). Effects of digital mammography uptake on downstream breast-related care among older women. Med Care 50(12):1053-1059. 3494765: PMC3494765 Link

Ji S, Roberts DW, Hartov A, Paulsen KD (2012). Intraoperative patient registration using volumetric true 3D ultrasound without fiducials. Med Phys 39(12):7540-7552. 3523742: PMC3523742 Link

Kaur M, Cole MD (2013). MYC acts via the PTEN tumor suppressor to elicit autoregulation and genome-wide gene repression by activation of the Ezh2 Methyltransferase. Cancer Res 73(2):695-705. PMC Link

Kodaman N, Aldrich MC, Smith JR, Signorello LB, Bradley K, Breyer J, Cohen SS, Long J, Cai Q, Giles J, Bush WS, Blot WJ, Matthews CE, Williams SM (2013). A small number of candidate gene SNPs reveal continental ancestry in African Americans. Ann Human Genet 77(1):56-66. PMC Link

Kohaar I, Porter-Gill P, Lenz P, Fu YP, Mumy A, Tang W, Apolo AB, Rothman N, Baris D, Schned AR, Ylaya K, Schwenn M, Johnson A, Jones M, Kida M, Silverman DT, Hewitt SM, Moore LE, Prokunina-Olsson L (2013). Genetic variant as a selection marker for anti-prostate stem cell antigen immunotherapy of bladder cancer. J Nat Cancer Instit 105(1):69-73. 3536639: PMC3536639 Link

Kukoyi A, Coker S, Lewis L, Nierenberg D (2013). Two cases of acute dexmedetomidine withdrawal syndrome following prolonged infusion in the intensive care unit: Report of cases and review of the literature. Hum Exp Toxicol 32(1):107-110. PMC Link

Lewis LD, Miller AA, Owzar K, Bies RR, Markova S, Jiang C, Kroetz DL, Egorin MJ, McLeod HL, Ratain MJ (2013). The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance). Pharmacogenet Geno 23(1):29-33. PMC Link

Lewis LD, Somogyi A, Loke YK, Ferro A, Cohen AF, Ritter JM (2013). Editors' pick 2012. Br J Clin Pharmacol 75(1):1-6. PMC Link

Liu H, Wang LE, Liu Z, Chen WV, Amos CI, Lee JE, Amfs Investigators QM, Investigators G, Iles MM, Law MH, Barrett JH, Montgomery GW, Taylor JC, Macgregor S, Newton Bishop JA, Hayward NK, Bishop DT, Mann GJ, Affleck P, Wei Q (2013, In press). Association between functional polymorphisms in genes involved in the MAPK signaling pathways and cutaneous melanoma risk. Carcinogenesis [Epub ahead of print]. PMC Link

Loftus RW, Brindeiro BS, Kispert DP, Patel HM, Koff MD, Jensen JT, Dodds TM, Yeager MP, Ruoff KL, Gallagher JD, Beach ML, Brown JR (2012). Reduction in intraoperative bacterial contamination of peripheral intravenous tubing through the use of a passive catheter care system. Anesth Analg 115(6):1315-1323. PMC Link

Loke YK, Cohen AF, Ferro A, Lewis LD, Ritter JM, Somogyi AA (2013). Editors' report, 2012. Br J Clin Pharmacol 75(2):301-302. PMC Link

Longacre MR, Defrancis GF, Fenzel M, Drake KM, Langeloh GE, Dalton MA (2013). Student scientists learn about energy balance through science museum-academic partnership. J Nutr Educ Behav 45(1):90-93. 3543499: PMC3543499 Link

Marotti JD, Schwab MC, McNulty NJ, Rigas JR, Delong PA, Memoli VA, Tsongalis GJ, Padmanabhan V (2013). Cytomorphologic features of advanced lung adenocarcinomas tested for EGFR and KRAS mutations: A retrospective review of 50 cases. Diagn Cytopathol 41(1):15-21. PMC Link

Martinez ME, Thompson P, Messer K, Ashbeck EL, Lieberman DA, Baron JA, Ahnen DJ, Robertson DJ, Jacobs ET, Greenberg ER, Cross AJ, Atkin W (2012). One-year risk for advanced colorectal neoplasia: U.S. versus U.K. Risk-stratification guidelines. A Int Med 157(12):856-864. PMC Link

McClure AC, Stoolmiller M, Tanski SE, Engels RC, Sargent JD (2013). Alcohol marketing receptivity, marketing-specific cognitions, and underage binge drinking. Alcohol Clin Exp Res 37 Suppl 1:E404-413. 3548023: PMC3548023 Link

Meehan KR, Talebian L, Tosteson TD, Hill JM, Szczepiorkowski Z, Sentman CL, Ernstoff MS (2013). Adoptive cellular therapy using cells enriched for NKG2D(+)CD3(+)CD8(+)T cells after autologous transplantation for Myeloma. Biol Blood Marrow Transplant 19(1):129-137. PMC Link

Michaelis LC, Saad A, Zhong X, Le-Rademacher J, Freytes CO, Marks DI, Lazarus HM, Bird JM, Holmberg L, Kamble RT, Kumar S, Lill M, Meehan KR, Saber W, Schriber J, Tay J, Vogl DT, Wirk B, Savani BN, Gale RP, Vesole DH, Schiller GJ, Abidi M, Anderson KC, Nishihori T, Kalaycio ME, Vose JM, Moreb JS, Drobyski W, Munker R, Roy V, Ghobadi A, Holland HK, Nath R, To LB, Maiolino A, Kassim AA, Giralt SA, Landau H, Schouten HC, Maziarz RT, Michael J, Kindwall-Keller T, Stiff PJ, Gibson J, Lonial S, Krishnan A, Dispenzieri A, Hari P (2013). Salvage second hematopoietic cell transplantation in Myeloma. Biol Blood Marrow Transplant. PMC Link

Mody K, Wallace JS, Stearns DM, Bowers G, Lacy SR, Levy NB, Zug KA, Lansigan F (2013, In press). CD30-positive cutaneous T-Cell lymphoma and response to Brentuximab Vedotin: 2 Illustrative cases. Clin Lymphoma Myeloma Leuk. PM C Link

Peters U, Jiao S, Schumacher FR, Hutter CM, Aragaki AK, Baron JA, Berndt SI, Bezieau S, Brenner H, Butterbach K, Caan BJ, Campbell PT, Carlson CS, Casey G, Chan AT, Chang-Claude J, Chanock SJ, Chen LS, Coetzee GA, Coetzee SG, Conti DV, Curtis KR, Duggan D, Edwards T, Fuchs CS, Gallinger S, Giovannucci EL, Gogarten SM, Gruber SB, Haile RW, Harrison TA, Hayes RB, Henderson BE, Hoffmeister M, Hopper JL, Hudson TJ, Hunter DJ, Jackson RD, Jee SH, Jenkins MA, Jia WH, Kolonel LN, Kooperberg C, Kury S, Lacroix AZ, Laurie CC, Laurie CA, Le Marchand L, Lemire M, Levine D, Lindor NM, Liu Y, Ma J, Makar KW, Matsuo K, Newcomb PA, Potter JD, Prentice RL, Qu C, Rohan T, Rosse SA, Schoen RE, Seminara D, Shrubsole M, Shu XO, Slattery ML, Taverna D, Thibodeau SN, Ulrich CM, White E, Xiang Y, Zanke BW, Zeng YX, Zhang B, Zheng W, Hsu L (2012, In press). Identification of G
genetic susceptibility loci for colorectal tumors in a genome-wide meta-analysis [Epub ahead of print]. Gastroenterology. PMC Link

Poklepovic A, Youseffian L, Winning M, Birdsell CA, Crosby NA, Ramakrishnan V, Ernstoff MS, Roberts JD (2013, In press). Phase I trial of bortezomib and dacarbazine in melanoma and soft tissue sarcoma. Invest New Drugs [Epub ahead of print]. PMC Link

Prokopetz JJ, Losina E, Bliss RL, Wright J, Baron JA, Katz JN (2012). Risk factors for revision of primary total hip arthroplasty: a systematic review. BMC musculoskeletal disorders 13:251. 3541060: PMC3541060 Link

Radcliff K, Kepler C, Hilibrand A, Rihn J, Zhao W, Lurie J, Tosteson T, Albert T, Weinstein J (2012). Epidural Steroid Injections Are Associated with Less Improvement in the Treatment of Lumbar Spinal Stenosis: A subgroup analysis of the SPORT. Spine (Phila Pa 1976). PMC Link

Reeves DB, Weaver JB (2012). Simulations of magnetic nanoparticle Brownian motion. J Appl Phys 112(12):124311. 3537703: PMC3537703 Link 

Sadetzki S, Bruchim R, Oberman B, Armstrong GN, Lau CC, Claus EB, Barnholtz-Sloan JS, Il'yasova D, Schildkraut J, Johansen C, Houlston RS, Shete S, Amos CI, Bernstein JL, Olson SH, Jenkins RB, Lachance D, Vick NA, Merrell R, Wrensch M, Davis FG, McCarthy BJ, Lai R, Melin BS, Bondy ML (2013, In press). Description of selected characteristics of familial glioma patients - Results from the Gliogene Consortium. Europ J Cancer [Epub ahead of print]. PMC Link

Saunders JE, Jastrzembski BG, Buckey JC, Enriquez D, Mackenzie TA, Karagas MR (2012). Hearing loss and heavy metal toxicity in a nicaraguan mining community: Audiological results and case reports. Audiology Neuro-Otology 18(2):101-113. PMC Link

Stan RV, Tse D, Deharvengt SJ, Smits NC, Xu Y, Luciano MR, McGarry CL, Buitendijk M, Nemani KV, Elgueta R, Kobayashi T, Shipman SL, Moodie KL, Daghlian CP, Ernst PA, Lee HK, Suriawinata AA, Schned AR, Longnecker DS, Fiering SN, Noelle RJ, Gimi B, Shworak NW, Carriere C (2012). The diaphragms of fenestrated endothelia: Gatekeepers of vascular permeability and blood composition. Dev Cell 23(6):1203-1218. 3525343: PMC3525343 Link

Strate LL, Erichsen R, Baron JA, Mortensen J, Pedersen JK, Riis AH, Christensen K, Sorensen HT (2013, In press). Heritability and familial aggregation of diverticular disease: A population-based study of twins and siblings. Gastroenterology [Epub ahead of print]. PMC Link

Thompson ME, Heimsath EG, Gauvin TJ, Higgs HN, Kull FJ (2013). FMNL3 FH2-actin structure gives insight into formin-mediated actin nucleation and elongation. Nat Struct Mol Biol 20(1):111-8. PMC Link

Toraya-Brown S, Sheen MR, Baird JR, Barry S, Demidenko E, Turk MJ, Hoopes PJ, Conejo-Garcia JR, Fiering S (2012). Phagocytes mediate targeting of iron oxide nanoparticles to tumors for cancer therapy. Integr Biol (Camb) 5(1):159-171. 3524361: PMC Link

Tuna M, Ju Z, Amos CI, Mills GB (2012). Soft tissue sarcoma subtypes exhibit distinct patterns of acquired uniparental disomy. BMC medical genomics 5:60. 3541987: PMC3541987 Link

Walsh KM, Amos CI, Wenzlaff AS, Gorlov IP, Sison JD, Wu X, Spitz MR, Hansen HM, Lu EY, Wei C, Zhang H, Chen W, Lloyd SM, Frazier ML, Bracci PM, Seldin MF, Wrensch MR, Schwartz AG, Wiencke JK (2012). Association study of nicotinic acetylcholine receptor genes identifies a novel lung cancer susceptibility locus near CHRNA1 in African-Americans. Oncotarget 3(11):1428-1438. PMC Link

Walsh KM, Gorlov IP, Hansen HM, Wu X, Spitz MR, Zhang H, Lu EY, Wenzlaff AS, Sison JD, Wei C, Lloyd SM, Chen W, Frazier ML, Seldin MF, Bierut LJ, Bracci PM, Wrensch MR, Schwartz AG, Wiencke JK, Amos CI (2012, In press). Fine-mapping of the 5p15.33, 6p22.1-p21.31 and 15q25.1 regions identifies functional and histology-specific lung cancer susceptibility loci in African-Americans. Cancer Epi Bio Prev [Epub ahead of print]. PMC Link

Wason SE, Seigne JD, Schned AR, Pais VM, Jr. (2012). Ureteroscopic biopsy of upper tract urothelial carcinoma using a novel ureteroscopic biopsy forceps.  Canadian J Urolo  19(6):6560-6565. PMC Link

Weber SC, Seto T, Olson C, Kenkare P, Kurian AW, Das AK (2012). Oncoshare: Lessons Learned from Building an Integrated Multi-institutional Database for Comparative Effectiveness Research. AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2012:970-978. 3540570: PMC3540570 Link

Wiener RS, Gould MK, Woloshin S, Schwartz LM, Clark JA (2012, In print). 'The thing is not knowing': Patients' perspectives on surveillance of an indeterminate pulmonary nodule. Health Expect [Epub ahead of print]. PMC Link

Woloshin S, Schwartz LM (2012). Getting to better prescription drug information. J Gen Intern Med 27(12):1582-1584. 3509306: PMC3509306 Link

Wu CC, Shete S, Jo EJ, Xu Y, Lu EY, Chen WV, Amos CI (2012). Whole-genome detection of disease-associated deletions or excess homozygosity in a case-control study of rheumatoid arthritis. Human Mol Genet [Epub ahead of print]. PMC Link

Xie G, Lu Y, Sun Y, Zhang SS, Keystone EC, Gregersen PK, Plenge RM, Amos CI, Siminovitch KA (2012, In press). Identification of the NF-kappaB activating protein-like locus as a risk locus for rheumatoid arthritis. Ann Rheumatic Dis [Epub ahead of print]. PMC Link

Xue Y, Liu X, Poplack S, Memoli VA (2012). Adenoid cystic carcinoma of the breast in reduction mammoplasty. Breast J 18(6):611-613. PMC Link