Recent Publications

Ahonen CL, Wasiuk A, Fuse S, Turk MJ, Ernstoff MS, Suriawinata AA, Gorham JD, Kedl RM, Usherwood EJ, Noelle RJ (2008). Enhanced efficacy and reduced toxicity of multifactorial adjuvants compared to unitary adjuvants as cancer vaccines. Blood. Link

Alabran JL, Cheuk A, Liby K, Sporn M, Khan J, Letterio J, Leskov KS (2008). Human Neuroblastoma Cells Rapidly Enter Cell Cycle Arrest and Apoptosis Following Exposure to C-28 derivatives of the Synthetic Triterpenoid CDDO. Cell Cycle 7 (5). Link

Andrew AS, Karagas MR, Nelson HH, Guarrera S, Polidoro S, Gamberini S, Sacerdote C, Moore JH, Kelsey KT, Demidenko E, Vineis P, Matullo G (2008). DNA repair polymorphisms modify bladder cancer risk: a multi-factor analytic strategy. Hum Hered 65 (2): 105-18. Link

Aronson JK, Cohen A, Lewis LD (2008). Clinical pharmacology--providing tools and expertise for translational medicine. Br J Clin Pharmacol 65 (2): 154-7. Link

Bak SP, Amiel E, Walters JJ, Berwin B (2008). Calreticulin requires an ancillary adjuvant for the induction of efficient cytotoxic T cell responses. Mol Immunol 45 (5): 1414-23. Link

Barber A, Zhang T, Sentman CL (2008). Immunotherapy with chimeric NKG2D receptors leads to long-term tumor-free survival and development of host antitumor immunity in murine ovarian cancer. J Immunol 180 (1): 72-8. Link

Belenky PA, Moga TG, Brenner C (2008). S. cerevisiae YOR071C encodes the high affinity nicotinamide Riboside transporter, Nrt1. J Biol Chem. Link

Benchabane H, Hughes EG, Takacs CM, Baird JR, Ahmed Y (2008). Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen. Development 135 (5): 963-71. Link

Blanke CD, Demetri GD, von Mehren M, Heinrich MC, Eisenberg B, Fletcher JA, Corless CL, Fletcher CD, Roberts PJ, Heinz D, Wehre E, Nikolova Z, Joensuu H (2008). Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT. J Clin Oncol 26 (4): 620-5. Link

Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE (2008). Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase activating protein abundant in skeletal muscle, is partially relieved by AMPK activation. J Biol Chem. Link

Clough-Gorr KM, Titus-Ernstoff L, Perry AE, Spencer SK, Ernstoff MS (2008). Exposure to sunlamps, tanning beds, and melanoma risk. Cancer Causes Control. Link

Cowling VH, Cole MD (2008). An N-Myc truncation analogous to c-Myc-S induces cell proliferation independently of transactivation but dependent on Myc homology box II. Oncogene 27 (9): 1327-32. Link

Dinkova-Kostova AT, Jenkins SN, Wehage SL, Huso DL, Benedict AL, Stephenson KK, Fahey JW, Liu H, Liby KT, Honda T, Gribble GW, Sporn MB, Talalay P (2008). A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice. Biochem Biophys Res Commun 367 (4): 859-65. Link

Diop SB, Bertaux K, Vasanthi D, Sarkeshik A, Goirand B, Aragnol D, Tolwinski NS, Cole MD, Pradel J, Yates JR, 3rd, Mishra RK, Graba Y, Saurin AJ (2008). Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control. EMBO Rep. Link

Donners MM, Beckers L, Lievens D, Munnix I, Heemskerk J, Janssen BJ, Wijnands E, Cleutjens J, Zernecke A, Weber C, Ahonen CL, Benbow U, Newby AC, Noelle RJ, Daemen MJ, Lutgens E (2008). The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling. Blood. Link

Dzierzak E, Speck NA (2008). Of lineage and legacy: the development of mammalian hematopoietic stem cells. Nat Immunol 9 (2): 129-36. Link

Eichler H, Nguyen XD, Roelen D, Celluzzi CM, McKenna D, Pamphilon D, Blair A, Read EJ, Takahashi TA, Szczepiorkowski ZM (2008). Multicenter study on in vitro characterization of dendritic cells. Cytotherapy 10 (1): 21-9. Link

Fishman M, Hunter TB, Soliman H, Thompson P, Dunn M, Smilee R, Farmelo MJ, Noyes DR, Mahany JJ, Lee JH, Cantor A, Messina J, Seigne J, Pow-Sang J, Janssen W, Antonia SJ (2008). Phase II trial of B7-1 (CD-86) transduced, cultured autologous tumor cell vaccine plus subcutaneous interleukin-2 for treatment of stage IV renal cell carcinoma. J Immunother (1997) 31 (1): 72-80. Link

Fuse S, Zhang W, Usherwood EJ (2008). Control of memory CD8+ T cell differentiation by CD80/CD86-CD28 costimulation and restoration by IL-2 during the recall response. J Immunol 180 (2): 1148-57. Link

Gorechlad JW, McCabe EB, Higgins JH, Likosky DS, Lewis PJ, Rosenkranz KM, Barth RJ, Jr. (2008). Screening for Recurrences in Patients Treated with Breast-Conserving Surgery: Is there a Role for MRI? Ann Surg Oncol. Link

Green KA, Okazaki T, Honjo T, Cook WJ, Green WR (2008). The programmed death-1 and interleukin-10 pathways play a down-modulatory role in LP-BM5 retrovirus-induced murine immunodeficiency syndrome. J Virol 82 (5): 2456-69. Link

Halter RJ, Hartov A, Paulsen KD (2008). A broadband high-frequency electrical impedance tomography system for breast imaging. IEEE Trans Biomed Eng 55 (2): 650-9. Link

Hanewinkel R, Sargent JD (2008). Exposure to smoking in internationally distributed American movies and youth smoking in Germany: a cross-cultural cohort study. Pediatrics 121 (1): e108-17. Link

Holick CN, Newcomb PA, Trentham-Dietz A, Titus-Ernstoff L, Bersch AJ, Stampfer MJ, Baron JA, Egan KM, Willett WC (2008). Physical activity and survival after diagnosis of invasive breast cancer. Cancer Epidemiol Biomarkers Prev 17 (2): 379-86. Link

Huang G, Zhang P, Hirai H, Elf S, Yan X, Chen Z, Koschmieder S, Okuno Y, Dayaram T, Growney JD, Shivdasani RA, Gilliland DG, Speck NA, Nimer SD, Tenen DG (2008). Erratum: PU.1 is a major downstream target of AML1 (RUNX1) in adult mouse hematopoiesis. Nat Genet 40 (2): 255. Link

Hughes DT, Martel PM, Kinlaw WB, Eisenberg BL (2008). The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. Cancer Invest 26 (2): 118-27. Link

Hunt K, Sweeting H, Sargent J, Lewars H, Cin SD, Worth K (2008). An examination of the association between seeing smoking in films and tobacco use in young adults in the west of Scotland: cross-sectional study. Health Educ Res. Link

Johnson DN, Egner PA, Obrian G, Glassbrook N, Roebuck BD, Sutter TR, Payne GA, Kensler TW, Groopman JD (2008). Quantification of Urinary Aflatoxin B1 Dialdehyde Metabolites Formed by Aflatoxin Aldehyde Reductase Using Isotope Dilution Tandem Mass Spectrometry. Chem Res Toxicol. Link

Karagas MR, Villanueva CM, Nieuwenhuijsen M, Weisel CP, Cantor KP, Kogevinas M (2008). Disinfection byproducts in drinking water and skin cancer? A hypothesis. Cancer Causes Control. Link

Kennedy ED, To T, Steinhart AH, Detsky A, Llewellyn-Thomas HA, McLeod RS (2008). Do patients consider postoperative maintenance therapy for Crohn's disease worthwhile? Inflamm Bowel Dis 14 (2): 224-35. Link

Koullourou T, Natrajan LS, Bhavsar H, Pope SJ, Feng J, Narvainen J, Shaw R, Scales E, Kauppinen R, Kenwright AM, Faulkner S (2008). Synthesis and spectroscopic properties of a prototype single molecule dual imaging agent comprising a heterobimetallic rhenium-gadolinium complex. J Am Chem Soc 130 (7): 2178-9. Link

Kroenke K, Shen J, Oxman TE, Williams JW, Jr., Dietrich AJ (2008). Impact of pain on the outcomes of depression treatment: results from the RESPECT trial. Pain 134 (1-2): 209-15. Link

Lefferts JA, Bartels CL, Tsongalis GJ (2008). Molecular oncology: current trends in diagnostics. Future Oncol 4 (1): 61-70. Link

Levesque AA, Fanous AA, Poh A, Eastman A (2008). Defective p53 signaling in p53 wild-type tumors attenuates p21waf1 induction and cyclin B repression rendering them sensitive to Chk1 inhibitors that abrogate DNA damage-induced S and G2 arrest. Mol Cancer Ther 7 (2): 252-62. Link

Li N, Singh S, Cherukuri P, Li H, Yuan Z, Ellisen LW, Wang B, Robbins D, Direnzo J (2008). Reciprocal Intra-Epithelial Interactions between TP63 and Hedgehog Signaling Regulate Quiescence and Activation of Progenitor Elaboration by Mammary Stem Cells. Stem Cells. Link

Liu MC, Demetri GD, Berry DA, Norton L, Broadwater G, Robert NJ, Duggan D, Hayes DF, Henderson IC, Lyss A, Hopkins J, Kaufman PA, Marcom PK, Younger J, Lin N, Tkaczuk K, Winer EP, Hudis CA (2008). Dose-escalation of filgrastim does not improve efficacy: Clinical tolerability and long-term follow-up on CALGB study 9141 adjuvant chemotherapy for node-positive breast cancer patients using dose-intensified doxorubicin plus cyclophosphamide followed by paclitaxel. Cancer Treat Rev. Link

Lollis SS, Roberts DW (2008). Robotic catheter ventriculostomy: feasibility, efficacy, and implications. J Neurosurg 108 (2): 269-74. Link

Loring GL, Christensen KC, Gerber SA, Brenner C (2008). Yeast Chfr homologs retard cell cycle at G1 and G2/M via Ubc4 and Ubc13/Mms2-dependent ubiquitination. Cell Cycle 7 (1): 96-105. Link

Ma Y, Feng Q, Pitha-Rowe I, Kitareewan S, Dmitrovsky E (2007). Gene profiling uncovers retinoid target genes. Methods Mol Biol 383: 101-21. Link

Mabaera R, Lowrey CH (2008). Response: 5-azacytidine induction of human fetal hemoglobin. Blood 111 (4): 2486. Link

Manning AL, Compton DA (2008). Structural and regulatory roles of nonmotor spindle proteins. Curr Opin Cell Biol 20 (1): 101-6. Link

Meehan KR, Wu J, Webber SM, Barber A, Szczepiorkowski ZM, Sentman C (2008). Development of a clinical model for ex vivo expansion of multiple populations of effector cells for adoptive cellular therapy. Cytotherapy 10 (1): 30-7. Link

Onega T, Duell EJ, Shi X, Wang D, Demidenko E, Goodman D (2008). Geographic access to cancer care in the U.S. Cancer 112 (4): 909-18. Link

Patel AS, Karagas MR, Pawlita M, Waterboer T, Nelson HH (2008). Cutaneous human papillomavirus infection, the EVER2 gene and incidence of squamous cell carcinoma: A case-control study. Int J Cancer. Link

Qi Y, Ranish JA, Zhu X, Krones A, Zhang J, Aebersold R, Rose DW, Rosenfeld MG, Carriere C (2008). Atbf1 is required for the Pit1 gene early activation. Proc Natl Acad Sci U S A 105 (7): 2481-6. Link

Saha S, Shipman SA (2008). Race-neutral versus race-conscious workforce policy to improve access to care. Health Aff (Millwood) 27 (1): 234-45. Link

Stern JE, Goldman MB, Hatasaka H, Mackenzie TA, Racowsky C, Surrey ES (2008). Optimizing the number of blastocyst stage embryos to transfer on day 5 or 6 in women 38 years of age and older: a Society for Assisted Reproductive Technology database study. Fertil Steril. Link

Thompson SL, Compton DA (2008). Examining the link between chromosomal instability and aneuploidy in human cells. J Cell Biol. Link

Titus-Ernstoff L, Dalton MA, Adachi-Mejia AM, Longacre MR, Beach ML (2008). Longitudinal study of viewing smoking in movies and initiation of smoking by children. Pediatrics 121 (1): 15-21. Link

Titus-Ernstoff L, Troisi R, Hatch EE, Hyer M, Wise LA, Palmer JR, Kaufman R, Adam E, Noller K, Herbst AL, Strohsnitter W, Cole BF, Hartge P, Hoover RN (2008). Offspring of Women Exposed In Utero to Diethylstilbestrol (DES): A Preliminary Report of Benign and Malignant Pathology in the Third Generation. Epidemiology 19 (2): 251-257. Link

To C, Kulkarni S, Pawson T, Honda T, Gribble GW, Sporn MB, Wrana JL, Di Guglielmo GM (2008). The synthetic triterpenoid CDDO-imidazolide alters TGFbeta -dependent signaling and cell migration by affecting the cytoskeleton and the polarity complex. J Biol Chem. Link

Tosteson AN, Stout NK, Fryback DG, Acharyya S, Herman BA, Hannah LG, Pisano ED (2008). Cost-effectiveness of digital mammography breast cancer screening. Ann Intern Med 148 (1): 1-10. Link

Vidyasagar R, Kauppinen RA (2008). (31)P magnetic resonance spectroscopy study of the human visual cortex during stimulation in mild hypoxic hypoxia. Exp Brain Res. Link

Zou W, Chen S, Liu X, Yue P, Sporn MB, Khuri FR, Sun SY (2007). c-FLIP Downregulation Contributes to Apoptosis Induction by the Novel Synthetic Triterpenoid methyl-2-cyano-3, 12-dioxooleana-1, 9-dien-28-oate (CDDO-Me) in Human Lung Cancer Cells. Cancer Biol Ther 6 (10). Link