Sentman Appointed Director of Immunology and Cancer Immunotherapy Research

August 27, 2009

Charles Sentman, PhD

Charles L. Sentman, PhD

Today Duane Compton, PhD, Associate Director for Basic Sciences, announced that Charles L. Sentman, PhD, has accepted appointment as Director of the Immunology and Cancer Immunotherapy Research Program (ICIP) of Norris Cotton Cancer Center.

The major goal of the Cancer Center Research Program structure is to foster the exchange of ideas, cooperation, and collaboration among cancer researchers in the broadest sense (laboratory, clinical, social), toward our mission of reducing the impact of cancer. Within that broad goal, the key focus is to optimize the translation of new knowledge into relevant therapeutic applications and cancer prevention mechanisms.

The ICIP was initiated in 1992 by Dr. William Green, Dean of Dartmouth Medical School, who led the Program until 2002. Drs. Randy Noelle and Richard Barth co-directed the ICIP from 2002 through two successful NCI Core Grant renewals. At present, the ICIP has 18 members and a strong record of peer-reviewed grant funding and publication in leading scientific journals. As ICIP Director, Dr. Sentman will continue the Program's commitment to bringing scientific discoveries into the clinic.

Dr. Sentman is an associate professor of microbiology and immunology, and has been an active member of the ICIP since 2002. Dr. Sentman's research interests have focused on natural killer (NK) cell recognition mechanisms and the role of NK cells as a part of the immune defenses. His laboratory has three major areas of research: chimeric NK cell receptors as immunotherapy, NK cells in tumor immunity, and human NK cell function in the female reproductive tract.