A National Cancer Institute Comprehensive Cancer Center

 
 

Cancer Care

 

 

Comprehensive Breast Program Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Breast-Female Clinical Trials
18F-Fluoride PET/CT Versus 99mTc-MDP Scanning for Detecting Bone Metastases: A Randomized, Multi-Center Trial to Compare Two Bone Imaging Techniques
Breast-Female
W0847
Seltzer
A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
Breast-Female
NCIC-MA.32
Chamberlin
A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients with 1-3 Positive Nodes, Hormone Receptor-Positive and HER2-Negative Breast Cancer with Recurrence Score (RS) of 25 or Less
Breast-Female
S1007
Chamberlin
A Prospective Study of Partial Breast Adjuvant Radiation Therapy After Resection of Borderline and Malignant Phyllodes Tumors
Breast-Female
D0929
Barth
A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer
Breast-Female
E2108
Schwartz
A Randomized, Double-Blind, Placebo-Controlled, Multi-Center Phase 3 Study of Denosumab as Adjuvant Treatment for Women with Early-Stage Breast Cancer at High Risk of Recurrence
Breast-Female
F11040
Schwartz
A Study to Evaluate the use of Supine MRI Images in Breast Conserving Surgery
Breast-Female
D0928
Barth
Alternative Breast Cancer Imaging Modalities: Correlation with Local Tissue Property Measurements and Histopathological Indices in Benign and Malignant Lesions
Breast-Female
D0404
Barth
An Open-Label Study of AMG 386 in Combination with Either Paclitaxel and Trastuzumab or Capecitabine and Lapatinib in Subjects with HER2-Positive Locally Recurrent or Metastatic Breast Cancer
Breast-Female
F0915
Kaufman
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Breast-Female
D0946
Bakitas
Monitoring and Predicting Breast Cancer Neoadjuvant Chemotherapy Response Using Diffuse Optical Spectroscopic Imaging (DOSI)
Breast-Female
ACRIN6691
Paulsen
Monitoring of Neoadjuvant Therapy in Locally-Advanced Breast Cancer
Breast-Female
D0605
Kaufman
NIR Hypoxia Imaging of Breast Tumor Response to Neoadjuvant Chemotherapy in Vivo
Breast-Female
D1025
Kaufman
PBX1 Expression and Endocrine Resistance in Subjects with Breast Cancer
Breast-Female
D1058
Schwartz
Participation Restrictions in Young-Middle Adult Rural Breast Cancer Survivors
Breast-Female
D1032
Hegel
Phase II Placebo-Controlled Trial of Lisinopril and Coreg CR® to Reduce Cardiotoxicity in Patients with Breast Cancer Receiving (Neo)Adjuvant Chemotherapy with Trastuzumab (Herceptin®)
Breast-Female
SCUSF0806
Schwartz
Randomized Phase II 2 x 2 Factorial Trial of the Addition of Carboplatin +/- Bevacizumab to Neoadjuvant Weekly Paclitaxel Followed by Dose- Dense AC in Hormone Receptor-Poor/HER2-Negative Resectable Breast Cancer
Breast-Female
C40603
Chamberlin
Breast-Male Clinical Trials
A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer
Breast-Male
E2108
Schwartz
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Breast-Male
D0946
Bakitas