x
Norris Cotton Cancer CenterNorris Cotton Cancer Center
In This Section

Gastrointestinal Oncology Program Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Anus Clinical Trials
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Anus
FED11061
Pace
Colon Clinical Trials
A Phase III Study of the Impact of a Physical Activity Program on Disease-Free Survival in Patients With High Risk Stage II or Stage III Colon Cancer: A Randomized Controlled Trial (CHALLENGE)
Colon
CO.21
Chamberlin
A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer
Colon
C80702
Ripple
A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab (IMC-1121B), in Advanced K-ras Wild-Type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy.
Colon
E7208
Hourdequin
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas
Colon
EA2142
Hourdequin
Randomized Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Colon
S1406
Hourdequin
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Colon
FED11061
Pace
Esophagus Clinical Trials
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery
Esophagus
R0436
Hartford
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Esophagus
D15113
Vergo
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas
Esophagus
EA2142
Hourdequin
Randomized Study of Early Palliative Care Integrated with Standard Oncology Care versus Standard Oncology Care Alone in Patients with Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Esophagus
A221303
Cullinan
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Esophagus
FED11061
Pace
Liver Clinical Trials
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Liver
D15113
Vergo
Randomized Study of Early Palliative Care Integrated with Standard Oncology Care versus Standard Oncology Care Alone in Patients with Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Liver
A221303
Cullinan
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Liver
FED11061
Pace
Treatment of Children with All Stages of Hepatoblastoma with Temsirolimus (IND#122782, NSC#683864) Added to High Risk Stratum Treatment
Liver
AHEP0731
Chaffee
Other Digestive Organ Clinical Trials
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Other Digestive Organ
D15113
Vergo
Randomized Study of Early Palliative Care Integrated with Standard Oncology Care versus Standard Oncology Care Alone in Patients with Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Other Digestive Organ
A221303
Cullinan
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Other Digestive Organ
FED11061
Pace
Pancreas Clinical Trials
A 3-Arm Phase 2 Double-Blind Randomized StudY of Gemcitabine, Abraxane? Plus PlacebO versuS GEMcitabIne, Abraxane? plus 1 or 2 TruncatEd Courses of Demcizumab in Subjects with 1st-Line Metastatic Pancreatic Ductal Adenocarcinoma
Pancreas
F15042
Hourdequin
A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/nab-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma
Pancreas
S1505
Hourdequin
A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic Neuroendocrine Tumors
Pancreas
E2211
Hourdequin
EP-GF-301: A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared with Fluorouracil (5-FU) in Patients with Metastatic Pancreatic Adenocarcinoma Previously Treated with Gemcitabine
Pancreas
F14028
Ripple
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Pancreas
D15113
Vergo
Nab-Paclitaxel (Abraxane) Plus Gemcitabine In Subjects With Locally Advanced Pancreatic Cancer (Lapc): An International, Open-Label, Multi-Center, Phase 2 Study (Lapact)
Pancreas
F15005
Ripple
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas
Pancreas
EA2142
Hourdequin
Randomized Phase II Study of Everolimus Alone Versus Everolimus Plus Bevacizumab in Patients with Locally Advanced or Metastatic Pancreatic Neuroendocrine Tumors
Pancreas
C80701
Hourdequin
Randomized Study of Early Palliative Care Integrated with Standard Oncology Care versus Standard Oncology Care Alone in Patients with Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Pancreas
A221303
Cullinan
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Pancreas
FED11061
Pace
Rectum Clinical Trials
A Phase II/III trial of Neoadjuvant FOLFOX, with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision
Rectum
N1048
Holubar
A Randomized Phase II Study of Irinotecan and Cetuximab with or without the Anti-Angiogenic Antibody, Ramucirumab (IMC-1121B), in Advanced K-ras Wild-Type Colorectal Cancer Following Progression on Bevacizumab-Containing Chemotherapy.
Rectum
E7208
Hourdequin
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas
Rectum
EA2142
Hourdequin
Randomized Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Rectum
S1406
Hourdequin
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Rectum
FED11061
Pace
Small Intestine Clinical Trials
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Small Intestine
D15113
Vergo
Randomized Phase II Study of Cisplatin and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas
Small Intestine
EA2142
Hourdequin
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Small Intestine
FED11061
Pace
Stomach Clinical Trials
Feasibility of a Creative Writing Intervention in an Advanced Cancer Population: A Single Arm, Cohort Study
Stomach
D15113
Vergo
Randomized Study of Early Palliative Care Integrated with Standard Oncology Care versus Standard Oncology Care Alone in Patients with Incurable Lung or Non-Colorectal Gastrointestinal Malignancies
Stomach
A221303
Cullinan
Randomized, Double-Blind, Phase 3 Study Evaluating TAS-102 Plus Best Supportive Care (BSC) Versus Placebo Plus BSC In Patients With Metastatic Gastric Cancer Refractory to Standard Treatments
Stomach
F16091
Hourdequin
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Stomach
FED11061
Pace

0