A National Cancer Institute Comprehensive Cancer Center

 
 

Cancer Care

 

 

Lung / Esophageal / Thoracic Cancer Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Esophagus Clinical Trials
A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel, Cisplatin, and Radiation for Patients With Esophageal Cancer Who Are Treated Without Surgery
Esophagus
R0436
Hartford
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Esophagus
D0946
Bakitas
Lung Clinical Trials
18F-Fluoride PET/CT Versus 99mTc-MDP Scanning for Detecting Bone Metastases: A Randomized, Multi-Center Trial to Compare Two Bone Imaging Techniques
Lung
W0847
Seltzer
A Phase I Dose Escalation Study of Hydroxyurea in Combination with SCH900776 in Advanced Malignant Solid Tumors
Lung
D1049
McGowan
A Phase II, Open-label, Multicenter, Randomized Study to Assess the Efficacy and Safety of GSK1120212 Compared with Docetaxel in 2nd Line Subjects with Targeted Mutations (KRAS,NRAS, RAF, MEK1) in Locally Advanced or Metastatic Nonsmall Cell Lung Cancer (NSCLC Stage IIIBwet-IV)
Lung
F11155
Rigas
A Randomized Double Blind Phase 3 Efficacy and Safety Study of PF-00299804 (Dacomitinib) versus Erlotinib for the Treatment of Advanced Non-Small Cell Lung Cancer Following Progression After, or Intolerance to, at Least One Prior Chemotherapy
Lung
F11096
Rigas
A Randomized Phase III Double-Blind Trial Evaluating Selective COX-2 Inhibition In COX-2 Expressing Advanced Non-Small Cell Lung Cancer
Lung
C30801
Dragnev
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Lung
D0946
Bakitas
Phase 3, Randomized, Open-Label Study Of The Efficacy And Safety Of Crizotinib Versus Pemetrexed/Cisplatin Or Pemetrexed/Carboplatin In Previously Untreated Patients With Non-squamous Carcinoma Of The Lung Harboring A Translocation Or Inversion Event Involving The Anaplastic Lymphoma Kinase (ALK) Gene Locus
Lung
F1057
Dragnev
Phosphoproteomic Patterns as a Novel Biomarker for Aurora and Polo-like Kinase Inhibitors in Non-Small Cell Lung Cancer
Lung
D1026
Rigas
Randomized, Multicenter, Double-Blind, Phase 3 Trial Comparing the Efficacy of Ipilimumab in Addition to Paclitaxel and Carboplatin versus Placebo in Addition to Paclitaxel and Carboplatin in Subjects with Stage IV/Recurrent Non-Small Cell Lung Cancer (NSCLC)
Lung
F11054
Rigas
Seamless Phase I/II Study of Stereotactic Lung Radiotherapy (SBRT) for Early Stage, Centrally Located, Non-Small Cell Lung Cancer (NSCLC) in Medically Inoperable Patients
Lung
R0813
Hartford
Other Respiratory and Intrathoracic Organs Clinical Trials
A Phase I Dose Escalation Study of Hydroxyurea in Combination with SCH900776 in Advanced Malignant Solid Tumors
Other Respiratory and Intrathoracic Organs
D1049
McGowan
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Other Respiratory and Intrathoracic Organs
D0946
Bakitas