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Norris Cotton Cancer CenterNorris Cotton Cancer Center
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Lymphoma / Leukemia Program Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Hodgkins Lymphoma Clinical Trials
Blood and Marrow Stem Cell Transplant Outcomes Database
Hodgkins Lymphoma
D11197
Meehan
Phase II Trial of Response-Adapted Therapy Based on Positron Emission Tomography (PET) for Bulky Stage I and Stage II Classical Hodgkin Lymphoma (HL)
Hodgkins Lymphoma
C50801
Bengtson
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Hodgkins Lymphoma
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Hodgkins Lymphoma
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Hodgkins Lymphoma
FED11061
Pace
Umbrella Long-Term Follow Up Protocol
Hodgkins Lymphoma
ALTE05N1
Chaffee
Leukemia, Other Clinical Trials
A Randomized Phase 2 Study of DACOGEN�(Decitabine) Plus JNJ-56022473 (Anti-CD123) Versus DACOGEN (Decitabine) Alone in Patients with AML who are not Candidates for Intensive Chemotherapy
Leukemia, Other
F16053
Lowrey
Blood and Marrow Stem Cell Transplant Outcomes Database
Leukemia, Other
D11197
Meehan
Classification of Newly Diagnosed Acute Lymphoblastic Leukemia
Leukemia, Other
AALL08B1
Chaffee
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Leukemia, Other
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Leukemia, Other
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Leukemia, Other
FED11061
Pace
TG Therapeutics, Inc. / A Multi-Center, Open-Label, Study to Evaluate the Safety and Efficacy of Ublituximab (TG-1101) in Combination with TGR-1202 for Patients Previously Enrolled in Protocol UTX-TGR-304
Leukemia, Other
F16066
Lansigan
Leukemia, not otherwise specified Clinical Trials
A Children's Oncology Group Protocol for Collecting and Banking Relapsed Acute Lymphoblastic Leukemia Research Specimens
Leukemia, not otherwise specified
AALL05B1
Chaffee
Blood and Marrow Stem Cell Transplant Outcomes Database
Leukemia, not otherwise specified
D11197
Meehan
Cytogenetic Studies in Acute Leukemia and Multiple Myeloma
Leukemia, not otherwise specified
C8461
Lowrey
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Leukemia, not otherwise specified
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Leukemia, not otherwise specified
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Leukemia, not otherwise specified
FED11061
Pace
Umbrella Long-Term Follow Up Protocol
Leukemia, not otherwise specified
ALTE05N1
Chaffee
Lymphoid Leukemia Clinical Trials
A Phase 2 Study to Assess the Safety and Efficacy of TGR-1202 in Patients with Chronic Lymphocytic Leukemia (CLL) who are Intolerant to Prior BTK or PI3K-Delta Inhibitor Therapy
Lymphoid Leukemia
F16097
Lansigan
A Phase 2, Open-Label Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacodynamics of GS-9973 in Subjects with Relapsed or Refractory Hematologic Malignancies
Lymphoid Leukemia
F15114
Lansigan
A Phase 3, Randomized, Study to Assess the Efficacy and Safety of Ublituximab in Combination with Ibrutinib Compared to Ibrutinib Alone, in Patients with Previously Treated High-Risk Chronic Lymphocytic Leukemia (CLL)
Lymphoid Leukemia
F15093
Lansigan
A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (BALL) Testing Clofarabine (IND# 73789, NSC# 606869) in the Very High Risk Stratum: A Groupwide Phase III Study
Lymphoid Leukemia
AALL1131
Chaffee
A Randomized Phase III Study of Bendamustine Plus Rituximab Versus Ibrutinib Plus Rituximab Versus Ibrutinib Alone in Untreated Older Patients ( e 65 Years of Age) with Chronic Lymphocytic Leukemia (CLL)
Lymphoid Leukemia
A041202
Lansigan
Blood and Marrow Stem Cell Transplant Outcomes Database
Lymphoid Leukemia
D11197
Meehan
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Lymphoid Leukemia
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Lymphoid Leukemia
B0944
Hill
Protocol to Obtain Blood Samples for Leukemia Research
Lymphoid Leukemia
D0905
Lowrey
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Lymphoid Leukemia
FED11061
Pace
Risk-Stratified Randomized Phase III Testing of Blinatumomab (NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL)
Lymphoid Leukemia
AALL1331
Chaffee
Screening Protocol to Determine High-risk Cytogenetic Features in Patients With Previously-treated CLL That May be Eligible for TG Therapeutics Trial UTX-IB-301
Lymphoid Leukemia
F16098
Lansigan
Multiple Myeloma Clinical Trials
Blood and Marrow Stem Cell Transplant Outcomes Database
Multiple Myeloma
D11197
Meehan
Differentiation agents and immunoproteasomes inhibitors for the treatment of multiple myeloma
Multiple Myeloma
D15103
Kisselev
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Multiple Myeloma
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Multiple Myeloma
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Multiple Myeloma
FED11061
Pace
Mycosis Fungoides Clinical Trials
Blood and Marrow Stem Cell Transplant Outcomes Database
Mycosis Fungoides
D11197
Meehan
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Mycosis Fungoides
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Mycosis Fungoides
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Mycosis Fungoides
FED11061
Pace
Myeloid and Monocytic Leukemia Clinical Trials
A Phase III Randomized Trial for Patients with de novo AML using Bortezomib and Sorafenib (IND#114480; NSC# 681239, NSC# 724772) for Patients with High Allelic Ratio FLT3/ITD
Myeloid and Monocytic Leukemia
AAML1031
Chaffee
AAML08B1 Biology Study of Transient Myeloproliferative Disorder(TMD)in Children with Down Syndrome(DS)
Myeloid and Monocytic Leukemia
AAML08B1
Chaffee
ACCL0933 A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML)
Myeloid and Monocytic Leukemia
ACCL0933
Chaffee
Blood and Marrow Stem Cell Transplant Outcomes Database
Myeloid and Monocytic Leukemia
D11197
Meehan
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Myeloid and Monocytic Leukemia
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Myeloid and Monocytic Leukemia
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Myeloid and Monocytic Leukemia
FED11061
Pace
Screening Protocol to Determine High-risk Cytogenetic Features in Patients With Previously-treated CLL That May be Eligible for TG Therapeutics Trial UTX-IB-301
Myeloid and Monocytic Leukemia
F16098
Lansigan
Non-Hodgkins Lymphoma Clinical Trials
A Phase 2, Open-Label Study Evaluating the Efficacy, Safety, Tolerability, and Pharmacodynamics of GS-9973 in Subjects with Relapsed or Refractory Hematologic Malignancies
Non-Hodgkins Lymphoma
F15114
Lansigan
A Phase 3B Randomized Study Of Lenalidomide (Cc-5013) Plus Rituximab Maintenance Therapy Followed By Lenalidomide Single-Agent Maintenance Versus Rituximab Maintenance In Subjects With Relapsed/Refractory Follicular,Marginal Zone Or Mantle Cell Lymphoma
Non-Hodgkins Lymphoma
F15004
Lansigan
A Randomized Phase Ii Trial Of Ofatumumab And Bendamustine Vs. Ofatumumab, Bortezomib (Nsc #681239, Ind #58443) And Bendamustine In Patients With Untreated Follicular Lymphoma
Non-Hodgkins Lymphoma
C50904
Lansigan
Blood and Marrow Stem Cell Transplant Outcomes Database
Non-Hodgkins Lymphoma
D11197
Meehan
Molecular Analysis for Therapy Choice (MATCH)
Non-Hodgkins Lymphoma
EAY131
Dragnev
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Non-Hodgkins Lymphoma
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Non-Hodgkins Lymphoma
B0944
Hill
Randomized Phase II Open Label Study of Lenalidomide R-CHOP (R2CHOP) vs RCHOP (Rituximab, Cyclophosphamide, Doxorubicin, Vincristine and Prednisone) in Patients with Newly Diagnosed Diffuse Large B Cell Lymphoma
Non-Hodgkins Lymphoma
E1412
Lansigan
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Non-Hodgkins Lymphoma
FED11061
Pace
Other Hematopoietic Clinical Trials
Blood and Marrow Stem Cell Transplant Outcomes Database
Other Hematopoietic
D11197
Meehan
Efficacy and Safety of Rivaroxaban Prophylaxis Compared with Placebo in Ambulatory Cancer Patients Initiating Systemic Cancer Therapy and at High Risk for Venous Thromboembolism
Other Hematopoietic
F15169
Roengvoraphoj
Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation with Unrelated Donors
Other Hematopoietic
B0942
Meehan
Patient and Caregiver Costs Following Hematopoietic Stem Cell Transplantation
Other Hematopoietic
D15165
Meehan
Protocol For A Research Database For Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-2002-0063)
Other Hematopoietic
B0943
Hill
Protocol For A Research Sample Repository For Allogeneic Hematopoietic Stem Cell Transplantation And Marrow Toxic Injuries (NMDP #IRB-1991-0002)
Other Hematopoietic
B0944
Hill
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Other Hematopoietic
FED11061
Pace

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