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Norris Cotton Cancer CenterNorris Cotton Cancer Center
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Neuro-Oncology Program Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Brain and Nervous System Clinical Trials
A Children's Oncology Group Protocol for Collecting and Banking Brain Tumor Research Specimens
Brain and Nervous System
ACNS02B3
Chaffee
A Phase II Basket Study of the Oral TRK Inhibitor LOXO-101 in Subjects with NTRK Fusion-Positive Tumors
Brain and Nervous System
F16078
Chamberlin
A Phase III Randomized, Double-Blind Placebo Controlled Study of Armodafinil (Nuvigil) to Reduce Cancer-Related Fatigue in Patients with High Grade Glioma
Brain and Nervous System
A221101
Rauschkolb
A Proof-of-Principle Study of Hyperbaric Oxygen as a Radiosensitizer Prior to Stereotactic Radiosurgery for Brain Metastases
Brain and Nervous System
D12129
Hartford
An Adaptive, Open-Label, Randomized Phase 2 Study of Abemaciclib as a Monotherapy and in Combination with Other Agents Versus Choice of Standard of Care (Gemcitabine or Capecitabine) in Patients with Previously Treated Metastatic Pancreatic Ductal Adenocarcinoma
Brain and Nervous System
F16179
Hourdequin
Efficacy of Carboplatin Administered Concomitantly with Isotretinoin as a Pro-Apoptotic Agent in Other than Average Risk Medulloblastoma/PNET Patients
Brain and Nervous System
ACNS0332
Chaffee
Evaluating the Expression Levels of MicroRNA-10b in Patients with Gliomas
Brain and Nervous System
D12160
Gaur
Immunologic Evaluation of Peripheral Blood
Brain and Nervous System
D0229
Lewis
Neuroblastoma Biology Studies
Brain and Nervous System
ANBL00B1
Chaffee
Neuropsychology and Neuroimaging in NeuroOncology: A Database Study
Brain and Nervous System
D14150
Wishart
Phase II Trial of SMO/AKT/NF2 Inhibitors in Progressive Meningiomas with SMO/AKT/NF2 Mutations
Brain and Nervous System
A071401
Ronan
Quantification of ALA-induced PpIX Fluorescence During Brain Tumor Resection
Brain and Nervous System
D13066
Roberts
Randomized Phase II Study of Irinotecan and Cetuximab with or without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
Brain and Nervous System
S1406
Hourdequin
Umbrella Long-Term Follow Up Protocol
Brain and Nervous System
ALTE05N1
Chaffee

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