A National Cancer Institute Comprehensive Cancer Center

 
 

Cancer Care

 

 

Neuro-Oncology Program Clinical Trials

A clinical trial is one of the final steps in a long and careful cancer research process that is looking for better ways to prevent, diagnose, or treat cancer. Clinical trials test new medical approaches in patients with cancer, and are important to developing new treatments for cancer. Many of the "standard treatments" that patients with cancer receive today were developed based on the results of previous clinical trials.

The following is a list of clinical trials with which this cancer care program is currently involved. Talk to your doctor to find out if a clinical trial is right for you.

Brain and Nervous System Clinical Trials
A Children's Oncology Group Protocol for Collecting and Banking Brain Tumor Research Specimens
Brain and Nervous System
ACNS02B3
Chaffee
A Phase III Randomized Study of Chimeric Anti-GD2 in High Risk Neuroblastoma following Myeloablative Therapy and Autologous Stem Cell Transplant (Companion Study to A3973)
Brain and Nervous System
ANBL0032
Chaffee
A Phase III Trial on Concurrent and Adjuvant Temozolomide Chemotherapy in Non-1p/19q Deleted Anaplastic Glioma. The CATNON Intergroup Trial.
Brain and Nervous System
R0834
Hartford
A Randomized Placebo-Controlled Trial of Armodafinil (Nuvigil) for Fatigue in Patients with Malignant Gliomas Undergoing Radiotherapy with or without Standard Chemotherapy Treatment
Brain and Nervous System
W1009
Fadul
A Randomized, Open-Label, Phase 3 Study Of Bms-936558 Vs. Everolimus In Subjects With Advanced Or Metastatic Clear-Cell Renal Cell Carcinoma Who Have Received Prior Anti-Angiogenic Therapy
Brain and Nervous System
F12154
Ernstoff
A proof-of-principle study of hyperbaric oxygen as a radiosensitizer prior to sterotactic radiosurgery for brain metastases
Brain and Nervous System
D12129
Hartford
An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The “ACT IV” Study)
Brain and Nervous System
F12019
Fadul
Coagulation activation in brain neoplasms
Brain and Nervous System
D12096
Ornstein
Early vs. Later Palliative Cancer Care: Clinical and Biobehavioral Effects
Brain and Nervous System
D0946
Bakitas
Efficacy of Carboplatin Administered Concomitantly with Isotretinoin as a Pro-Apoptotic Agent in Other than Average Risk Medulloblastoma/PNET Patients
Brain and Nervous System
ACNS0332
Chaffee
Evaluating the Expression Levels of MicroRNA-10b in Patients with Gliomas
Brain and Nervous System
D12160
Gaur
Immunologic Evaluation of Peripheral Blood
Brain and Nervous System
D0229
Ernstoff
Neuroblastoma Biology Studies
Brain and Nervous System
ANBL00B1
Chaffee
Phase I/Randomized Phase II Double Blind Study of Either Dasatinib or Placebo Combined with Bevacizumab in Recurrent Glioblastoma
Brain and Nervous System
N0872
Fadul
Phase II Trial Of Observation For Low-Risk Meningiomas And Of Radiotherapy For Intermediate and High-Risk Meningiomas
Brain and Nervous System
R0539
Hartford
Phase III Study of Radiation Therapy With or Without Temozolomide for Symptomatic or Progressive Low-Grade Gliomas
Brain and Nervous System
E3F05
Fadul
Protocol for Use of Brain Tumor Tissue for Research
Brain and Nervous System
D0004
Fadul
Reducing Disparities in Health for Vulnerable Populations in NH and VT: Journey Forward Cancer Survivor Care Planning in the Rural Northeast
Brain and Nervous System
FED11061
Pace
Umbrella Long-Term Follow Up Protocol
Brain and Nervous System
ALTE05N1
Chaffee
Vaccination of Patients with Newly Diagnosed Glioblastoma Using Autologous Tumor Lysate and Montanide Emulsion for Derivation of Tumor Specific Hybridomas
Brain and Nervous System
W12209
Fadul