Adjuvant Androgen Deprivation Versus Mitoxantrone Plus Prednisone Plus Androgen Deprivation in Selected High Risk Prostate Cancer Patients Following Radical Prostatectomy, Phase III
RATIONALE: Hormones can stimulate the production of prostate cancer cells. Hormone therapy
may fight prostate cancer by reducing the production of androgens. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. It is not yet known whether hormone therapy plus mitoxantrone and prednisone is more
effective than hormone therapy alone for prostate cancer.
PURPOSE: This randomized phase III trial is studying hormone therapy, mitoxantrone, and
prednisone to see how well they work compared to hormone therapy alone in treating patients
who have undergone radical prostatectomy for prostate cancer.
View more details from ClinicalTrials.gov.
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