Lipoprotein Lipase Expression in Chronic Lymphocytic Leukemia
The investigators hypothesize that Lipoprotein Lipase (LPL) expression on Chronic
Lymphocytic Leukemia (CLL) cells will predict a more aggressive clinical course. The results
from this proposal will validate the use of a novel antibody developed at
Dartmouth-Hitchcock in CLL and will predict CLL patients that have a more aggressive form of
the disease. The investigators work will also provide direct evidence that LPL is expressed
on CLL cells and provides a critical source of fatty acids required by the CLL cells to grow
and survive. Fatty acid metabolism may become a therapeutic target in CLL in the future.
View more details from ClinicalTrials.gov.
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