A Randomized Phase III Trial Of Cisplatin And Tumor Volume Directed Irradiation Followed By Carboplatin And Paclitaxel Vs. Carboplatin And Paclitaxel For Optimally Debulked, Advanced Endometrial Carcinoma
This randomized phase III trial studies carboplatin and paclitaxel to see how well they work
with or without cisplatin and radiation therapy in treating patients with stage I, stage II,
stage III, or stage IVA endometrial cancer. Drugs used in chemotherapy, such as carboplatin,
paclitaxel, and cisplatin, work in different ways to stop the growth of tumor cells, either
by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy
x-rays and other types of radiation to kill tumor cells. Giving chemotherapy and radiation
therapy after surgery may kill any tumor cells that remain after surgery. It is not yet
known whether carboplatin and paclitaxel are more effective with or without cisplatin and
radiation therapy in treating patients with endometrial cancer.
View more details from ClinicalTrials.gov.
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