Phase II Placebo-Controlled Trial of Lisinopril and Coreg CR? to Reduce Cardiotoxicity in Patients with Breast Cancer Receiving (Neo)Adjuvant Chemotherapy with Trastuzumab (Herceptin?)
RATIONALE: Lisinopril or Coreg CR®, may help reduce side effects caused by trastuzumab. It
is not yet known whether lisinopril or Coreg CR® are more effective than a placebo in
reducing side effects caused by trastuzumab.
PURPOSE: This phase II trial is studying lisinopril and Coreg CR® to see how well they work
compared with a placebo in reducing side effects in patients with HER2-positive breast
cancer receiving trastuzumab.
View more details from ClinicalTrials.gov.
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