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iron sucrose (injection)

Pronunciation: EYE urn SOO krose

Brand: Venofer

What is the most important information I should know about iron sucrose injection?

Multum donot

You should not receive this medication if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis.

Before you receive iron sucrose injection, tell your doctor if you have low blood pressure, hepatitis, or if you have received many blood transfusions in the past.

Iron sucrose injection can make it harder for your body to absorb iron medications you take by mouth. Tell your doctor if you are taking iron supplements or other iron-based oral medications.

What is iron sucrose injection?

Iron sucrose is a form of the mineral iron. Iron is important for many functions in the body, especially for the transport of oxygen in the blood.

Iron sucrose injection is used to treat iron deficiency anemia in people with kidney disease. It is usually given with another medication to promote the growth of red blood cells (such as Aranesp, Epogen, or Procrit).

Multum donot

This medication is not for treating other forms of anemia not caused by iron deficiency.

Iron sucrose injection may also be used for other purposes not listed in this medication guide.

What should I discuss with my healthcare provider before I receive iron sucrose injection?

Multum donot

You should not receive this medication if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use iron sucrose injection:

  • low blood pressure;
  • hepatitis; or
  • if you have received many blood transfusions.

FDA pregnancy category B. Iron sucrose injection is not expected to be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Multum nobrfeed

It is not known whether iron sucrose injection passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use iron sucrose injection?

Iron sucrose injection is given as an injection through a needle placed into a vein or directly into a dialysis line. You will receive this injection in a clinic, hospital, or dialysis setting.

To be sure this medication is helping your condition and not causing harmful effects, your blood may need to be tested often. This will help your doctor determine how long to treat you with iron sucrose injection. Do not miss any scheduled appointments.

What happens if I miss a dose?

Call your doctor if you miss an appointment for your iron sucrose injection.

What happens if I overdose?

Multum emt

Seek emergency medical attention if you think you have received too much of this medicine.

Overdose symptoms may include dizziness, headache, nausea, vomiting, stomach pain, joint or muscle pain, swelling, numbness or tingling, trouble breathing, slow heart rate, weak pulse, fainting, slow breathing (breathing may stop).

These symptoms may also occur if the medication is infused too quickly.

What should I avoid while using iron sucrose injection?

Follow your doctor's instructions about any restrictions on food, beverages, or activity while you are using iron sucrose injection.

What are the possible side effects of iron sucrose injection?

Multum emt

Get emergency medical help if you have any of these signs of an allergic reaction: hives, itching; wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Multum emt

Tell your caregivers right away if you have a serious side effect such as:

  • chest pain;
  • feeling like you might pass out;
  • swelling in your hands, ankles, or feet;
  • trouble breathing; or
  • dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, chest pain, shortness of breath, uneven heartbeats, seizure).

Less serious side effects may include:

  • muscle cramps;
  • weakness, tired feeling;
  • dizziness, anxiety, headache;
  • nausea, vomiting, stomach pain;
  • diarrhea, constipation;
  • ear pain;
  • sore throat, sinus pain or congestion;
  • decreased sense of taste;
  • joint pain; or
  • pain, swelling, burning, or irritation around the IV needle.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect iron sucrose injection?

Iron sucrose injection can make it harder for your body to absorb iron medications you take by mouth. Tell your doctor if you are taking iron supplements or other iron-based oral medications, such as:

  • ferrous fumarate (Feostat, Ferrets, Ferrocite, Hemocyte, Ircon, Tandem);
  • ferrous gluconate (Ferate, Fergon); and
  • ferrous sulfate (Feosol, Fer-Gen-Sol, Slow Fe), and others.

This list is not complete and there may be other drugs that can interact with iron sucrose injection. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

Where can I get more information?

Your doctor or pharmacist can provide more information about iron sucrose injection.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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