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Rh Disease

National Organization for Rare Disorders, Inc.

Important

It is possible that the main title of the report Rh Disease is not the name you expected. Please check the synonyms listing to find the alternate name(s) and disorder subdivision(s) covered by this report.

Synonyms

  • Congenital Anemia of Newborn
  • Erythroblastosis Fetalis
  • Erythroblastosis Neonatorum
  • Hemolytic Anemia of Newborn
  • Hemolytic Disease of Newborn
  • Icterus Gravis Neonatorum
  • Rh Factor Incompatibility
  • Rh Incompatibility
  • Rhesus Incompatibility

Disorder Subdivisions

  • None

General Discussion

Rh disease or Rh incompatibility (also known as erythroblastosis fetalis) occurs when a woman with Rh-negative blood conceives a child with Rh-positive blood. Red blood cells are destroyed (hemolysis) because of this incompatibility, leading to anemia and other symptoms in the infant. Symptoms vary in severity among affected infants and may include an unusual yellowish coloration of the skin (jaundice); swelling of the chest and abdomen due to the accumulation of fluid (edema); and/or a pale appearance of the skin. In more severe cases, affected infants may have experience life-threatening complications. Rh disease occurs only when a mother's blood is Rh-negative and her baby's blood is Rh-positive.

Resources

NIH/National Heart, Lung and Blood Institute

P.O. Box 30105

Bethesda, MD 20892-0105

Tel: (301)592-8573

Fax: (301)251-1223

Email: nhlbiinfo@rover.nhlbi.nih.gov

Internet: http://www.nhlbi.nih.gov/



National Perinatal Information Center

225 Chapman Street

Suite 200

Providence, RI 02905

Tel: (401)274-0650

Fax: (401)455-0377

Email: web_admin@npic.org

Internet: http://www.npic.org



National Perinatal Association

2000 North Beauregard Street, 6th Floor

Alexandria, VA 22311

USA

Fax: (703)684-5968

Tel: (888)971-3295

Email: npa@nationalperinatal.org

Internet: http://www.nationalperinatal.org



Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

TDD: (888)205-3223

Internet: http://rarediseases.info.nih.gov/GARD/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to MyD-H, the Dartmouth-Hitchcock patient portal. You must be a registered MyD-H user for the Lebanon, Manchester, or Nashua locations to access this site.

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  4/14/2008

Copyright  1986, 1989, 1992, 1995, 1997, 2006 National Organization for Rare Disorders, Inc.

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