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Transverse Myelitis

National Organization for Rare Disorders, Inc.

Important

It is possible that the main title of the report Transverse Myelitis is not the name you expected.

Disorder Subdivisions

  • Ascending Myelitis
  • Brown-Sequard Syndrome
  • Concussion Myelitis
  • Foix-Alajouanine Myelitis
  • Subacute Necrotizing Myelitis
  • Funicular Myelitis
  • Systemic Myelitis

General Discussion

Summary

Transverse myelitis (TM) is a rare inflammatory disease causing injury to the spinal cord with varying degrees of weakness, sensory alterations, and autonomic dysfunction (the part of the nervous system that controls involuntary activity, such as the heart, breathing, the digestive system, and reflexes).



Introduction

The first cases of acute myelitis were described in 1882 and were attributed to vascular lesions and acute inflammatory events. In England between 1922 and 1923 more than 200 postvaccinial cases were noted as complications of the smallpox and rabies vaccines. Later reports revealed that TM was post-infectious in nature, and agents including measles, rubella and mycoplasma were directly isolated from patient's spinal fluid. The term "acute transverse myelitis" was first used by an English neurologist in 1948 to describe a case of rapidly progressive paraparesis with a thoracic sensory level, occurring as a postinfectious complication of pneumonia. The Transverse Myelitis Consortium Working Group delineated diagnostic criteria for disease-associated TM and idiopathic TM along with a framework to differentiate TM from non-inflammatory myelopathies in 2002.

Resources

Transverse Myelitis Association

1787 Sutter Parkway

Powell, OH 43065-8806

USA

Tel: (614)766-1806

Email: info@myelitis.org

Internet: http://www.myelitis.org



Spinal Cord Society

19051 County Hwy. 1

Fergus Falls, MN 56537

USA

Tel: (218)739-5252

Fax: (218)739-5262

Email: scs-nc@nc.rr.com

Internet: http://www.spinalcordsociety.com



Academy of Spinal Cord Injury Professionals, Inc.

206 South Sixth Street, Springfield, IL 62701

Springfield, IL 62701

USA

Tel: (217)753-1190

Fax: (217)525-1271

Email: acheatham@firminc.com

Internet: http://www.academyscipro.org/



National Spinal Cord Injury Association

75-20 Astoria Blvd

Jackson Heights, NY 11370

USA

Tel: (718)803-3782

Tel: (800)962-9629

Email: info@spinalcord.org

Internet: http://www.spinalcord.org



NIH/National Institute of Neurological Disorders and Stroke

P.O. Box 5801

Bethesda, MD 20824

Tel: (301)496-5751

Fax: (301)402-2186

Tel: (800)352-9424

TDD: (301)468-5981

Internet: http://www.ninds.nih.gov/



Christopher & Dana Reeve Foundation

636 Morris Turnpike, Suite 3A

Short Hills, NJ 07078

USA

Tel: (973)379-2690

Fax: (973)912-9433

Tel: (800)225-0292

Email: prc@ChristopherReeve.org

Internet: http://www.christopherreeve.org



Genetic and Rare Diseases (GARD) Information Center

PO Box 8126

Gaithersburg, MD 20898-8126

Tel: (301)251-4925

Fax: (301)251-4911

Tel: (888)205-2311

TDD: (888)205-3223

Internet: http://rarediseases.info.nih.gov/GARD/



For a Complete Report

This is an abstract of a report from the National Organization for Rare Disorders (NORD). A copy of the complete report can be downloaded free from the NORD website for registered users. The complete report contains additional information including symptoms, causes, affected population, related disorders, standard and investigational therapies (if available), and references from medical literature. For a full-text version of this topic, go to www.rarediseases.org and click on Rare Disease Database under "Rare Disease Information".

The information provided in this report is not intended for diagnostic purposes. It is provided for informational purposes only. NORD recommends that affected individuals seek the advice or counsel of their own personal physicians.

It is possible that the title of this topic is not the name you selected. Please check the Synonyms listing to find the alternate name(s) and Disorder Subdivision(s) covered by this report

This disease entry is based upon medical information available through the date at the end of the topic. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.

For additional information and assistance about rare disorders, please contact the National Organization for Rare Disorders at P.O. Box 1968, Danbury, CT 06813-1968; phone (203) 744-0100; web site www.rarediseases.org or email orphan@rarediseases.org

Last Updated:  9/13/2012

Copyright  1988, 1989, 1996, 2004, 2012 National Organization for Rare Disorders, Inc.

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