Contact sensitizers are a form of
immunotherapy. Immunotherapy triggers your
immune system to kill the virus causing the
wart. This destroys the wart.
are required to trigger your body's immune system with a contact
The contact sensitizer is put on a small area
of your arm or back. Your skin should become red, swollen, itchy, or blistered.
This kind of skin reaction is a sign that the contact sensitizer will work. The
next time the sensitizer is applied to your skin, your body's immune system
will react to it, and the affected area will develop an allergic (immune)
After a few days, the same sensitizer is applied to the
wart (diluted for common warts and concentrated for plantar warts). Repeat
treatments with increasingly concentrated sensitizer are made every week or so
until the immune reaction has cleared the wart.
Why It Is Used
Contact sensitizers are sometimes used
to treat warts that have been resistant to other treatments.
How Well It Works
One review of studies reports that
DNCB removed warts in 80% of the people using it compared to 38% in people
placebo.1 Talk to your doctor
about how well his or her choice of contact sensitizers has worked in clinical
Loo SK, Tang WY (2009). Warts (non-genital), search
date June 2008. Online version of BMJ Clinical Evidence: http://www.clinicalevidence.com.
How this information was developed to help you make better health decisions.