Irinotecan is an antitumor drug that interferes with how cancer
cells multiply. The dose is based on your body size. The type and extent of a
cancer determines the exact dose and schedule for using this drug. Irinotecan
intravenous (IV) drug.
Why It Is Used
Irinotecan is used to treat cancer of the cervix, colon, or rectum.
It may also be used to treat non–small-cell lung cancer.
How Well It Works
Irinotecan is an effective antitumor drug for many
people. But the type and extent of a cancer determines how
effectively this drug slows or stops the growth of cancer cells in the
body. Irinotecan is often used in combination with other chemotherapy
drugs, making the other drugs more effective than they are by
Side effects of irinotecan include:
Shortness of breath.
counts, which may increase your risk of infection or
Nausea, vomiting, and loss of
Diarrhea or constipation.
Increased sweating and increased
Temporary hair loss.
Changes in kidney and liver function tests.
See Drug Reference for a full list of side effects. (Drug Reference
is not available in all systems.)
Venook A (2005). Critical evaluation of current
treatments of metastatic colorectal cancer. Oncologist,
How this information was developed to help you make better health decisions.