Looking for Mastectomy Alternatives

Dartmouth cancer researchers Michael Sporn, MD, and Karen Liby, PhD, have been awarded $250,000 from the Breast Cancer Research Foundation to continue their research into promising new agents for preventing ER-negative breast cancer.

Focus article photo

Michael Sporn, MD

Sporn and Liby ultimately hope to improve quality of life for women at exceptionally high risk for devel­oping breast cancer by finding an effective and safe preventive drug regimen that would eliminate the need for bilateral pro­phylactic mastectomy. This is the third year of their study, and to date they have found that several new chemopreventive agents are effective drugs for suppressing the development of ER-negative breast cancer in experimental laboratory models.

April 27, 2011