Research Centers




Naomi Aronson, PhD
Naomi Aronson, PhD
Executive Director, Technology Evaluation Center
Blue Cross & Blue Shield Association

Dr. Aronson is the Executive Director of the Blue Cross and Blue Shield Association Technology Evaluation Center (TEC). Dr. Aronson has overseen TEC's development as a nationally recognized technology assessment program and an Evidence-based Practice Center (EPC) of the Agency for Healthcare Research and Quality (AHRQ). She has directed over 300 technology assessments and 20 evidence reports for AHRQ. Dr. Aronson is a member of the Methodology Committee of the Patient-Centered Outcomes Research Institute (PCORI).

Dr. Aronson is a member of the Health Technology Assessment International Health Policy Forum, the Institute of Medicine Genomics Roundtable, the Steering Committee of the Chicago-Area DEcIDE Research Center, and the National Business Group on Health Committee on Evidence-Based Benefit Design. Previously, she has represented the private sector on a U.S. Agency for International Development Team providing technical assistance to the Hungarian government on building evidence-based medicine capacity and also served on the Ontario Health Technology Assessment Evaluation Review Team. She was a member of the Institute of Medicine Forum on Drug Discovery Translation and Development, and a review committee co-chair for the International Society for Pharmacoeconomics and Outcomes Research Annual Meeting.

Prior to joining TEC, Dr. Aronson was a member of the Northwestern University faculty, specializing in the sociology of science and medicine. She also was a post-doctoral fellow in the Science, Technology and Society Program at the Massachusetts Institute of Technology and received research awards from the National Science Foundation and the American Council of Learned Societies. Dr. Aronson's academic research focused on how the organization of scientific specialties in biomedical and clinical research affects the process of scientific discovery.

Peter Bach, MD
Peter B. Bach, MD
Attending Physician, Director of Center for Health Policy and Outcomes
Memorial Sloan-Kettering Cancer Center

Dr. Bach's main research interests cover healthcare policy, particularly as relates to Medicare, racial disparities in cancer care quality, and lung cancer epidemiology. His research examining quality of care for Medicare beneficiaries has demonstrated that blacks do not receive as high quality care as whites when diagnosed with lung cancer, and that the aptitude and resources of primary care physicians who treat blacks are inferior, when compared to primary care physicians who primarily treat whites. In 2007 he was the senior author on a study demonstrating that care in Medicare is highly fragmented, with the average beneficiary seeing multiple primary care physicians and specialists. His work in lung cancer epidemiology has focused on the development and utilization of lung cancer prediction models that can be used to determine what lung cancer events populations of elderly smokers will experience over a period of time. His healthcare policy analysis includes investigations into Medicare's approaches to cancer payment, as well as developing models of alternative reimbursement, payment systems, and coverage policies. He is funded by grants from the National Institute of Aging, a contract from the NCI, and philanthropic sources. He formerly served a Senior Adviser to the Administrator of the Centers for Medicare and Medicaid Services. He serves on several national committees, including the Institute of Medicine's National Cancer Policy Forum, and the Committee on Performance Measurement of the National Committee on Quality Assurance. He chairs the Technical Expert Panel that is developing measures of cancer care quality for CMS. Along with publishing in the medical literature, Dr. Bach's opinion pieces have appeared in numerous lay new outlets, including the New York Times, the Wall Street Journal, Forbes Online and National Public Radio.

William Black, MD
William C. Black, MD
Professor of Radiology and of Community & Family Medicine, Geisel School of Medicine at Dartmouth; Dartmouth-Hitchcock, and The Dartmouth Institute for Health Policy and Clinical Practice; Co-Director, Center for Comparative Effectiveness Research in Cancer Imaging, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth

Dr. Black is a Professor of Radiology and of Community and Family Medicine at Dartmouth Hitchcock Medical Center (DHMC) and member of The Dartmouth Institute. His clinical area of expertise is chest radiology and he has research interests in screening and decision making. As the site Principal Investigator at DHMC and a member of the Executive Committee, Dr. Black has played a major role in the design, execution, and analysis of the National Lung Screening Trial (NLST). He is currently leading the cost-effectiveness analysis related to lung cancer screening in the NLST and a consultant to the Lung Group of the Cancer Intervention and Surveillance Network (CISNET), which is modeling the effects of alternative strategies of lung cancer screening on the US population. Dr. Black is also the Director of the Outcomes and Economics Core Laboratory of the American College of Radiology Imaging Network (ACRIN) and a principal investigator on the NCI Grand Opportunities grant "Comparative Effectiveness of Advanced Imaging in Cancer", which established the multi-institutional Center for Comparative Effectiveness Research in Cancer Imaging. Through the Center, he is examining the effects of incidental findings on medical utilization in the Medicare eligible subset of the NLST.

Dennis Fryback, PhD
Dennis G. Fryback, PhD
Professor Emeritus, Department of Population Health Sciences
University of Wisconsin–Madison

Dr. Fryback has a PhD in mathematical psychology from The University of Michigan where he trained in human decision making and decision analysis with application in medical decision making. An active member of the University of Wisconsin faculty in Population Health Sciences and in Industrial and Systems Engineering for 33 years, he developed and taught graduate courses in clinical decision analysis, systems evaluation, medical technology assessment, and health outcomes measurement.

His research interests are broad, covering health technology assessment and cost-effectiveness analysis (especially emphasizing evaluation of imaging technologies), applied Bayesian analysis, systems simulation applied to cancer epidemiology, and measuring health-related quality of life in individuals and in populations. Most recently he led a collaborative research program comparing indexes of health-related quality of life in older US adults and establishing population norms for these indexes.

He has chaired the Health Care Technology Study Section and served as member of the National Advisory Council for the US Agency for Healthcare Research and Quality. He chaired the Board of Scientific Counselors for the US National Library of Medicine of the National Institutes of Health, and was a member both of the US Preventive Services Task Force (1992-96) and the US Panel on Cost-effectiveness in Health and Medicine (1993-96). During its first 6 years he was active in the American College of Radiology Imaging Network, chairing the outcomes measurement and cost-effectiveness committee.  He was a founding member of the Society for Medical Decision Making and has served as that society's President as well as Editor-in-Chief of its journal, Medical Decision Making.  In 2000, he was elected to the Institute of Medicine of the US National Academies.

Since 2008, when he retired as an active faculty member and moved to southern California, Dr. Fryback has been concentrating his research writing efforts on population applications of, and methodological work relating to, health-related quality-of-life measures.  He continues to work with the US National Academies. He was a member of the Panel to Advance a Research Program on the Design of National Health Accounts for the National Research Council's Committee on National Statistics (see Accounting for Health and Health Care: Approaches to measuring the sources and costs of their improvement, The National Academies Press, Washington DC, 2010), and a contributor to a National Research Council workshop on common metrics in the social sciences (The Importance of Common Metrics for Advancing Social Science Theory and Research: A workshop summary, National Academies Press, Washington DC, 2011).  He has been a member of several Institute of Medicine committees, including the Committee on Summarizing Population Health (report 1998); Committee to Evaluate Measures of Health Benefits for Environmental, Health, and Safety Regulation (report 2006); Committee on Identifying and Prioritizing New Preventive Vaccines for Development (report in preparation 2012).

Ilana Gareen, PhD
Ilana Gareen, PhD
Assistant Professor of Epidemiology
Brown University Center for Statistical Sciences and ACRIN Biostatistics and Data Management Center

Dr. Gareen is an epidemiologist and has been a member of the faculty of Brown's Center for Statistical Sciences since 1999. Her research focuses on evaluating new and existing medical technologies. She has examined the impact of noncompliance on the results of screening trials and is exploring methods to estimate screening effects in the absence of noncompliance. She is particularly interested in the correlation between health system and participant characteristics and compliance. Dr. Gareen has been working on collecting data in the National Lung Screening Trial (NLST) related to the unintentional downstream consequences of medical interventions, especially the impact that these new technologies may have on the medical system, on patient health, and on patient quality of life. She is Co-Chair for ACRIN 6654 (NLST), a co-investigator on the National Oncologic Pet Registry (NOPR), a co-investigator on the Grand Opportunity grant Comparative Effectiveness of Advanced Imaging in Cancer, and a co-investigator on the AHRQ-funded RESCUE (Randomized Evaluation of Patients with Stable Angina Comparing Utilization of Noninvasive Examinations) study. She is a member of the NLST study-wide executive committee, the ACRIN NLST Executive Committee. Dr. Gareen oversees the performance of medical chart abstraction for the ACRIN arm of the NLST and for RESCUE. She is the lead investigator in the quality of life portion of NLST and RESCUE and directs the collection of these data, and she is working on several sub-studies of smoking cessation for NLST, and coordinates an ancillary study of the impact of perceived risk of lung cancer.

G. Scott Gazelle, MD, MPH, PhD
G. Scott Gazelle, MD, MPH, PhD
Professor of Radiology, Massachusetts General Hospital
Professor of Health Policy & Management, Harvard Medical School
Director, MGH Institute for Health Policy Assessment, Harvard School of Public Health

Dr Gazelle is Professor of Radiology at Harvard Medical School and Professor in the Department of Health Policy and Management at the Harvard School of Public Health. He serves as Director of the MGH Institute for Technology Assessment and the Dana-Farber/Harvard Cancer Center Program in Cancer Outcomes Research Training. He is also Vice Chair for Faculty Development and Associate Vice-Chair for Research in the MGH Department of Radiology.

Dr. Gazelle received his B.A. from Dartmouth College, and his MD from Case Western Reserve University School of Medicine. He completed a Radiology residency at University Hospitals of Cleveland, where he also served as Chief Resident. Following residency, he completed a fellowship in Abdominal Imaging and Interventional Radiology at the Massachusetts General Hospital, and then joined the faculty at the MGH in the Division of Abdominal Imaging and Interventional Radiology. In 1996, he received an M.P.H. from the Harvard School of Public Health, where he majored in Health Care Management. In 1999, he received a PhD in Health Policy from Harvard University.

Dr. Gazelle has been President of the Association of University Radiologists, the Radiology Research Alliance and the New England Roentgen Ray Society. He has also been Chair of the American College of Radiology Commission on Research and Technology Assessment, the RSNA Research Development Committee and Director of Partners Radiology. He currently serves on the RSNA R&E Foundation Board of Trustees. Dr. Gazelle is nationally and internationally known for his research evaluating the benefits, costs, and appropriate use of new medical technologies. Locally, he has lead efforts at Partners HealthCare System to improve quality and safety in radiology and to develop approaches that can be used to measure and document performance improvement. Dr. Gazelle has authored more than 200 scientific articles, published 2 textbooks and presented numerous papers, lectures, and workshops nationally and internationally.

Constantine Gatsonis, PhD
Constantine Gatsonis, PhD
Director, Center for Statistical Sciences
Brown University

Dr. Gatsonis is Henry Ledyard Goddard University Professor of Biostatistics, and chair of the Department of Biostatistics at Brown University. Dr. Gatsonis is a leading authority on the evaluation of diagnostic and screening tests and has extensive involvement in the development of methods for medical technology assessment and health services and outcomes research. He is the founding editor-in-chief of the journal Health Services and Outcomes Research Methodology. Dr. Gatsonis' current research portfolio in Comparative Effectiveness Research is focused on the evaluation of diagnostic and screening tests. His work includes methodologic and substantive research projects addressing the role of diagnostic imaging in cancer and cardiovascular disease. He served on the IOM Committee on Comparative Effectiveness Research Prioritization, and is involved in CER initiatives with the RSNA.

Dr. Gatsonis is Network Statistician of the American College of Radiology Imaging Network (ACRIN), an NCI-funded collaborative group conducting multi-center studies of diagnostic imaging and image-guided therapy for cancer. He is the chief statistician of the Digital Mammography Imaging Screen Trial (DMIST), ACRIN's arm of the National Ung Screening Trial (NLST), and of several other studies of the role imaging for diagnosis and staging, monitoring, and prediction of response to therapy. A growing component of ACRIN's research agenda is focused on CER.

Bruce Hillman, MD
Bruce J. Hillman, MD
Professor of Radiology, University of Virginia
Editor-in-Chief, Journal of the American College of Radiology
Founder and Chief Science Officer, ACT Image Metrix

Dr. Hillman is the Professor of Radiology and Public Health Sciences at the University of Virginia. He was Chair of the Department of Radiology during 1992- 2003. He now serves as both the Founder and Chief Scientific Officer of ACR Image Metrix, a contract research organization owned by the American College of Radiology (2007-present), and as Founding Editor of the Journal of the American College of Radiology (2003-present). During 1999-2007, he was the Founding PI and Chair of the American College of Radiology Imaging Network (ACRIN), an NCI-funded clinical trials cooperative group that conducted more than 30 multi-center studies of imaging under his leadership.

Dr. Hillman was educated at Princeton University (BA '69) and the University of Rochester (MD '73). He received his radiology training at the Peter Bent Brigham Hospital. He trained in health services research and policy at the RAND Corporation as a Pew Fellow during 1984-5. His first appointment was at the University of Arizona (1978-1991.

Dr. Hillman has published 176 peer-reviewed journal articles and more than 140 book chapters, review articles, editorials, and texts. His book with Jeff Goldsmith, The Sorcerer's Apprentice: How Medical Imaging is Changing Health Care, was published by Oxford University Press in 2010. He has presented more than 40 honorary lectures, including both the RSNA Pendergrass New Horizons Lecture and the ARRS Caldwell Lecture. His principal research interests have focused on health services research and policy and clinical trials. His research into self-referral for diagnostic imaging altered AMA ethics policies and influenced federal and state legislation.

Dr. Hillman has been President of five radiological societies and is a member of the American College of Radiology Board of Chancellors (1995-present). Dr. Hillman was Editor-in-Chief of Investigative Radiology (1989-1994), and was the Founding Editor-in-Chief of Academic Radiology (1994-1997). Among the many honors Dr. Hillman has received are Honorary Fellowship in the French Society of Radiology, the Royal Australian and New Zealand College of Radiology and the Royal College of Radiologists. He was the 2007 Radiological Society of North America Outstanding Researcher and has received the Gold Medals of the Association of University Radiologists, the Society of Uroradiology, and the Radiological Society of North America.

Bruce Hillner, MD
Bruce E. Hillner, MD
Eminent University Scholar and Professor of Medicine
Virginia Commonwealth University

Bruce E. Hillner, MD, is a general internist (doctor for adults) and cancer researcher. He is an Eminent University Scholar and Professor of Medicine at the Virginia Commonwealth University and the Massey Cancer Center, Richmond, VA (U.S.).

He is an internationally recognized expert in outcomes research in oncology, especially breast cancer. He has addressed a variety of 'outcomes' issues including technology assessment, patterns of care, quality of care indicators, costs and, most commonly, cost-effectiveness analyses. He has >100 peer reviewed publications. He has served on numerous peer review (AHRQ, NCI, American Cancer Society) panels, committees of the American Society of Clinical Oncology and U.S. cooperative cancer trial groups.

He is also the National (U.S.) Chair of the National Oncology PET Registry. This registry was the first such program under the Medicare Coverage with Evidence Development to lead to a major expansion in Medicare coverage policy of emerging technologies (2009).

His current academic goals are to use his methodological and oncology clinical expertise as the national health focus shifts to Comparative Effective Research. His recent commentaries with his long-time collaborator Tom Smith include a New Engl J Med (2001) Sounding Board "Bending the Cost Curve of Cancer Care" and a J Clin Oncol (2010) "Efficacy Does Not Necessarily Translate to Cost-Effectiveness—A Case Study in the Challenges Associated with 21st Century Cancer Drug Pricing".

Louis B. Jacques, MD
Director, Coverage and Analysis Group
Centers for Medicare and Medicaid Services

Dr. Jacques joined CMS in 2003 and has been director of the Coverage and Analysis Group since October 2009. The group reviews evidence and develops Medicare national coverage policy. Prior to his arrival at CMS, Dr. Jacques was the Associate Dean for Curriculum at Georgetown University School of Medicine, where he retains a faculty appointment. He served on a number of university committees including the Executive Faculty, Committee on Admissions and the Institutional Review Board. He previously worked in the Palliative Care program at Georgetown Lombardi Comprehensive Cancer Center, where he covered the gynecologic oncology service.

Emmett Keeler, PhD
Emmett Keeler, PhD
Senior Mathematician

Dr. Keeler (PhD Mathematics, Harvard) is a Professor in the Pardee RAND Graduate School, and an Adjunct Professor at the UCLA Public Health School, where he has taught cost-effectiveness and decision analysis for many years. He led the multi-site Improving Chronic Illness Care Evaluation. He analyzed health outcomes and episodes of spending for the RAND Health Insurance Experiment. He has worked on the theory and practice of decision analyses and cost effectiveness analysis of clinical procedures and cancer screening. He led the RAND analysis and cost-effectiveness resource core of the UCLA Older Americans Independence Center. With RAND co-authors, he studied the cost of poor health habits, which led to a prize-winning paper and a well-regarded book. An elected member of the Institute of Medicine, he participated in IOM committees on the economic costs of uninsurance, the use of health measures in regulatory analysis, national health accounts, and geographic variation in health care spending.

Larry Kessler, ScD
Larry Kessler, ScD
Chair and Professor, Department of Health Services
University of Washington

In January 2009, Dr. Kessler was appointed as Professor and Chair of the Department of Health Services at the University of Washington, School of Public Health. In this role he directs over 60 faculty members who provide education in a wide variety of health services disciplines leading to degrees in public health, including a PhD program, Masters of Public Health, Masters of Health Administration, and a recently developed undergraduate major in public health. Prior to joining the faculty at UW, he spent 30 years working for the federal government, first at the National Institute of Mental Health, then at the National Cancer Institute, and most recently at the US Food and Drug Administration's Center for Devices and Radiological Health. He obtained his ScD degree in Operations Research from the Johns Hopkins School of Public Health in 1978.

He has published over 100 peer-reviewed journal articles, as well as numerous book chapters and government reports. His research has concentrated on applications of quantitative methods and health services research to problems in surveillance and public health.

Joseph Lau, MD
Joseph Lau, MD
Director, Evidence Based Practice Center
Tufts Medical Center

Dr. Lau is Professor of Medicine and Professor of Clinical and Translational Science at the Institute for Clinical Research and Health Policy Studies at the Tufts Medical Center. He also holds an adjunct professor appointment at the Tufts Friedman School of Nutrition Science and Policy. He is the director of the AHRQ designated Tufts Evidence-based Practice Center (EPC) since 1997. He also served as the methodological director of the National Kidney Foundation's KDIGO evidence-based clinical practice guidelines program from 2000 to 2009. His research interest is in the areas of meta-analysis, evidence-based medicine and development of clinical practice guidelines. With ARRA funding the Tufts EPC has focused on comparative effectiveness reviews of diagnostic tests, imaging technologies, and medical devices in the past 3 years. He has directed the production of over 60 evidence reports and technology assessments, and published over 200 articles on the methodological aspects of systematic review and meta-analysis as well as numerous systematic reviews across a wide range of biomedical and healthcare topics. He serves on the editorial board of Biomed Central Medical Research Methodology, Journal of Nutrition, and Journal of Research Synthesis Methodology. He has served as a member of an FDA advisory committee and as a member of an FAO/WHO workshop to develop a framework to perform nutrient risk assessment. He was a member of an IOM committee to establish a framework to evaluate the safety of dietary supplements and the committee on standards for clinical practice guidelines.

Pamela Marcus, PhD
Pamela Marcus, PhD
Epidemiologist, Division of Cancer Control and Population Science
National Cancer Institute

Dr. Marcus is an Epidemiologist with the Health Services and Economics Branch in the Division of Cancer Control and Population Sciences at the National Cancer Institute. She has worked in the field of cancer epidemiology for over 20 years. She has published extensively in the areas of cancer screening and risk factor identification. Her research interests include cancer screening methodology and clinical trial operations. She recently completed her tenure as an Assistant Project Officer on NCI's National Lung Screening Trial, on which she oversaw issues concerning study protocol and management. Currently she is Lead Program Scientist for PROSPR, an NCI initiative designed to examine and optimize community-based screening for breast, cervical, and colorectal cancer. She also provides scientific leadership for other NCI-sponsored activities, including the Breast Cancer Surveillance Consortium, the breast component of the International Cancer Screening Network, and a joint US-China workshop to examine possible cancer prevention and screening collaborations between the two countries.

Diana Miglioretti, PhD
Diana Miglioretti, PhD
Senior Investigator
Group Health Research Institute

Dr. Miglioretti is a Senior Scientific Investigator in the Biostatistics Unit at Group Health Research Institute and an Affiliate Professor in the Biostatistics Department at the University of Washington. She received her PhD from the Department of Biostatistics at Johns Hopkins University in 2000. Since starting her position at Group Health in 2000, Dr. Miglioretti has been actively involved in both methodological and collaborative research. Dr. Miglioretti’s primary methodological research interests are in multilevel and latent variable models, longitudinal and clustered data analysis, and the evaluation of screening and diagnostic tests. The majority of her collaborative research is in the areas of breast cancer screening and radiation exposure from medical imaging. She serves on American College of Radiology’s National Mammography database planning committee and is faculty member for the Radiologic Society of North America’s clinical trials methodology workshop. Dr. Miglioretti was the PI of the Statistical Coordinating Center for the National Cancer Institute (NCI) funded Breast Cancer Surveillance Consortium (BCSC) from 2005-2011 and is now PI of a 5-year NCI contract, "Breast Cancer Surveillance Consortium Data Resource Statistical Coordinating Center," to maintain and share the BCSC pooled data with the broader research community. She is the contact PI and director of the Biostatistics and Data Management Core for the multi-site BCSC Program Project "Risk-Based Breast Cancer Screening in Community Settings" (NCI P01 CA154292), contact PI of the GO grant "Comparative Effectiveness of Breast Cancer Imaging Strategies in Community Practice" (NCI RC2CA148577), and PI of the Statistical Coordinating Center for the American Cancer Society and NCI co-funded grant "Assessing and Improving Radiologists Interpretive Performance." She is also the PI or site PI for a several grants examining trends in medical imaging and associated radiation exposure.

Bruce Quinn, MD
Bruce Quinn, MD
Senior Health Policy Specialist
Foley, Hoag, LLP

Dr. Quinn is a national expert on Medicare policy, the impact of health reform on innovation, and the crafting of successful clinical access strategies within the US healthcare reimbursement system. He has worked successfully with both large and small companies in overcoming hurdles to commercialization through negotiation, understanding insightful ways to use the existing system to advantage, and the mechanisms of policy change. Since 2008, Dr. Quinn has been a full time business strategist working with attorney and policy teams for healthcare and life sciences clients in the firm's Government Strategies practice. Dr. Quinn travels nationwide to speak on health reform issues and publishes actively, recently writing several peer reviewed policy articles on the impact of personalized medicine. He has worked with stakeholder groups on Medicare's national policies for advanced medical imaging.

Before joining Foley Hoag LLP, he was the regional Medicare medical director for the California Part B program, with authority for final coverage decisions for approximately 15% of the U.S. Medicare program. Earlier in his career, Dr. Quinn was a physician executive in the Health & Life Sciences division of Accenture, working with the pharma, biotech, and genomics industries. Dr. Quinn is a board-certified pathologist. As a physician-scientist on the faculty of Northwestern University School of Medicine, he led pathology research for Northwestern's NIH-funded Alzheimer Research Center. Earlier, he also held academic positions at New York University School of Medicine and the UCLA Center for Health Sciences and is the author or co-author on 30 scientific publications. He holds an MBA from the Kellogg School of Northwestern University.

Donald Rucker, MD
Donald W. Rucker, MD
Vice President, Chief Medical Officer
Siemens Healthcare USA

Dr. Rucker is the Vice President and Chief Medical Officer of Siemens Healthcare USA, the healthcare division of Siemens. He is a graduate of Harvard College and the University of Pennsylvania School of Medicine with Board Certifications in Internal Medicine and Emergency Medicine. He holds a Masters in Medical Computer Science and an MBA, both from Stanford. Dr. Rucker came to Siemens from Beth Israel Deaconess Medical Center in Boston where he was the first full-time Emergency Department attending and from Datamedic Corporation where he co-developed the first Microsoft Windows based electronic medical record. At Siemens, Dr. Rucker led the team that designed the computerized physician order entry workflow that, as installed at Cincinnati Children's Hospital, won the 2003 HIMSS Nicholas Davies Award for the best hospital computer system in the US. Dr. Rucker recently finished two terms on the Board of Commissioners of the Certification Commission for Healthcare Information Technology. He is actively engaged in many of the Congressional and federal agency healthcare policy discussions affecting the Siemens diagnostic product portfolio. He also practices emergency medicine in the University of Pennsylvania Health System.

Barry Siegel, MD
Barry A. Siegel, MD
Professor of Radiology and of Medicine, Director, Division of Nuclear Medicine, Mallinckrodt Institute of Radiology
Washington University

Dr. Siegel is currently Professor of Radiology and Medicine at Washington University School of Medicine, Director of the Division of Nuclear Medicine at Mallinckrodt Institute of Radiology, and a member of the University's Alvin J. Siteman Cancer Center. He has been at Washington University since 1962, when he matriculated as an undergraduate. He subsequently attended medical school, followed by medical internship and radiology and nuclear medicine residency at Washington University and was appointed Director of the Division of Nuclear Medicine in 1973.

Throughout his career, Dr. Siegel has been active in nuclear medicine research, and has made contributions related to the diagnosis of pulmonary embolism, the detection of thrombosis, and oncological applications of radionuclide tracers. His current research efforts are focused on uses of positron emission tomography for cancer diagnosis and staging, as well as predicting and monitoring the tumor response to therapy. He also devotes considerable time to the development and conduct of multicenter clinical trials in the arena of cancer imaging in his role as Group Deputy Co-chair for Molecular Imaging of the American College of Radiology Imaging Network (ACRIN). Since 2005, he has devoted much of his time to the development and operation of the National Oncologic PET Registry.

A prolific writer and editor, with over 300 journal articles, book chapters, and books to his credit, Dr. Siegel is also actively involved as an editorial board member for several journals, and served from 1988 to 2002 as the Editor In Chief of the Professional Self-Evaluation Program (the "Syllabus Series") published by the American College of Radiology.

Dr. Siegel is active in government affairs, having served as a consultant and advisory committee chair for the Food and Drug Administration. He is also a past chairman of the Nuclear Regulatory Commission's Advisory Committee on the Medical Use of Isotopes, and a consultant to the NRC. In 2003, the Society of Nuclear Medicine awarded him the Georg Charles de Hevesy Nuclear Pioneer Award for outstanding contributions to nuclear medicine, and in 2008 he received the Peter Valk Distinguished Clinical Scientist Award from the Academy of Molecular Imaging.

Dr. Siegel is a respected clinician at Washington University Medical Center and has been selected by the Mallinckrodt Institute's radiology residents as an outstanding teacher. The Washington University Alumni Association named a Distinguished Alumni Scholarship in his honor in 1997 and honored him with its Alumni Faculty Award in 2004.

Chris Sistrom, MD, MPH
Chris Sistrom, MD, MPH
Associate Professor and Chief Information Officer, Department of Radiology
University of Florida

After serving in the U.S. Army Signal Corps as a cryptographer from 1973-1977, Dr. Sistrom obtained his undergraduate degree in Computer Science (1980) from the University of Oregon in Eugene. He attended at Oregon Health Sciences University (1984) and completed residency at the University of Virginia (1988). He is now Associate Chairman of Radiology, Chief Information Officer for Radiology, and Associate Professor at the University of Florida. Dr. Sistrom obtained an MPH degree in epidemiology and health policy in 2003 from the University of Florida, and recently completed a PhD in Health Services Research there. The topic of his dissertation was Factors Affecting Outpatient Imaging Utilization in Primary Care Practice. The research goal was to quantify and model various factors that affect the intensity and mixture of outpatient imaging performed on primary care patients. The resulting models will be useful in practitioner profiling at institutional and regional levels. The eventual goal is to produce a 'Map of Imaging' along the lines of the Dartmouth Atlas of Healthcare and to create risk-adjusted population based estimates of optimal and appropriate imaging utilization.

Natasha Stout, PhD
Natasha Stout, PhD
Instructor, Department of Population Medicine
Harvard Medical School

Dr. Stout is an Instructor in Population Medicine at the Harvard Medical School. She is a member of the Center for Health Decision Science at the Harvard School of Public Health. Her research agenda focuses on applying decision-analytic modeling methods to better understand how existing and emerging medical technologies are implemented and used to their fullest capacity to improve population health. Her methodological interests are in the development and calibration of population-based discrete-event simulation models of disease. She has particular expertise in the area of breast cancer natural history modeling. Since its inception in 2000, Natasha has been participating in the National Cancer Institute's Cancer Intervention and Surveillance Modeling Network (CISNET), a collaboration of independent modeling teams formed to address unresolved policy questions in cancer control. She is the current recipient of an American Cancer Society career development award to evaluate MRI as it is used for breast cancer screening in the community. The research involves analyzing electronic health data from a large medical group practice to understand test performance and to integrate the results into a decision-analytic model for policy evaluation. Natasha is on the Board of Trustees of the Society for Medical Decision Making and coordinates the Society's career development and mentoring programs. Dr. Stout received a B.A. in Mathematics from Oberlin College, and an M.S. in Industrial Engineering focusing on Operations Research and Decision Science and PhD in Population Health Sciences from the University of Wisconsin. Prior to her PhD, she worked at Epic Systems, a firm that develops healthcare information software.

Sean Tunis, MD, MSc
Sean Tunis, MD, MSc
President & CEO
Center for Medical Technology Policy

Dr. Tunis is the President and CEO of the Center for Medical Technology Policy in Baltimore, Maryland. CMTP's main objective is to improve the quality, relevance and efficiency of clinical research by providing a neutral forum for collaboration among experts, stakeholders and decision makers.  Dr. Tunis was a member of the Institute of Medicine Committee on Initial National Priorities for Comparative Effectiveness Research.  He advises a wide range of domestic and international public and private health care organizations on issues of comparative effectiveness, evidence based medicine, clinical research, reimbursement, and health technology policy.

Through September of 2005, Dr. Tunis was the Chief Medical Officer at the Centers for Medicare and Medicaid Services (CMS), where he had lead responsibility for clinical policy for the Medicare and Medicaid programs. Previously he served as the Director of the Health Program at the Congressional Office of Technology Assessment and as a health policy advisor to the U.S. Senate, where he worked on pharmaceutical and device policy issues.

Dr. Tunis trained at the University of California in Los Angeles and the University of Maryland in Internal Medicine and Emergency Medicine, and holds adjunct faculty positions at the Center for Health Policy at Stanford University, the Department of Internal Medicine at the Johns Hopkins School of Medicine, and the Department of Surgery at the University of California at San Francisco.

Anna N. A. Tosteson, ScD
Anna N.A. Tosteson, ScD
Professor of Medicine, of Community and Family Medicine, and of The Dartmouth Institute; Co-Director, Center for Comparative Effectiveness Research in Cancer Imaging, Norris Cotton Cancer Center, Geisel School of Medicine at Dartmouth

Dr. Tosteson is a senior faculty member at The Dartmouth Institute of Health Policy and Clinical Practice where she leads the Comparative Effectiveness Research (CER) Program and is affiliated with both the Center for Health Policy Research and the Center for Informed Choice. Through the CER Program, she directs Norris Cotton Cancer Center's Office of Cancer Comparative Effectiveness Research and Dartmouth's Multidisciplinary Clinical Research Center in Musculoskeletal Diseases.

Dr. Tosteson did her undergraduate training in statistics and biometry at Cornell University and her graduate studies in biostatistics and health decision science at Harvard University. Her research uses decision-analytic modeling, economic evaluation and preference-based measures of health-related quality of life to address clinical and health policy issues in cancer, musculoskeletal diseases and women's health. She is an active participant in national and international groups that focus on the comparative effectiveness and economic evaluation of both new and established health care technologies, including the American College of Radiology Imaging Network (ACRIN). She is principal investigator for several ongoing comparative effectiveness research studies sponsored by NIH and AHRQ, including the NCI Grand Opportunities grant, "Comparative Effectiveness of Advanced Imaging in Cancer", which established the multi-institutional Center for Comparative Effectiveness Research in Cancer Imaging.

Tor Tosteson, ScD
Tor D. Tosteson, ScD
Professor of Community & Family Medicine (Biostatistics), Geisel School of Medicine at Dartmouth; Dartmouth-Hitchcock, and The Dartmouth Institute for Health Policy and Clinical Practice

Dr. Tosteson is a senior faculty member in the Section of Biostatistics and Epidemiology and in the Dartmouth Institute of Health Policy and Clinical Practice. He serves as Director of three methodological cores: the Biostatistics Shared Resource for the Norris Cotton Cancer Center; the Biostatistics and Quantitative Methodology Core for SYNERGY, the Dartmouth Center for Clinical and Translational Research; and the Methodology Core of the Dartmouth Multidisciplinary Clinical Research Center in Musculoskeletal Diseases. He has worked extensively in imaging applications in cancer diagnosis, treatment, and outcomes research. His educational activities include directing the biostatistics component of the new Dartmouth Quantitative Biomedical Sciences graduate program and serving as PI (multiple) for an R25 post-doctoral training grant in Quantitative Biomedical Sciences. He conducts statistical research in measurement error methods, image based research, instrumental variables and clinical trials.