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Norris Cotton Cancer Center
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Research Interests

As part of a National Cancer Institute-designated research and treatment center, the Melanoma / Skin Cancer Program conducts research at Dartmouth and in partnership with other national research organizations into the biology, causes, prevention, and treatment of melanoma.

The Program integrates information from our basic science laboratories, from epidemiology and prevention research, and from clinical research and trials, in an effort to understand—and one day eliminate melanoma.

Current research projects include:

  • Case control study of melanoma to compare those with melanoma to those without, in order to understand why some people develop the disease while others do not
  • Community skin cancer prevention research, to develop new approaches to education and prevention
  • Melanoma biology, to understand how melanoma starts and grows
  • New approaches to treatment including:
    • Cytokine therapy, which activates the immune system and can help shrink metastatic melanoma in some patients
    • Metronomic therapy, which uses frequent, low-dose chemotherapy to attack the blood system that feeds the melanoma
    • Adoptive T-cell therapy, which transfuses lymphocytes to enhance immunity against melanoma
  • Tumor and blood bank, to identify markers of melanoma for use in the development of new therapies
  • Clinical trials, including participation in the Cancer Immunotherapy Trials Network
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