Diagnostic Performance of Fluorescein as an Intraoperative Brain Tumor Biomarker: Correlation with Preoperative MR, ALA-induced PpIX Fluorescence, and Histopathology
This clinical research will evaluate the diagnostic potential of fluorescein as visualized
through an operating microscope relative to 1) contrast enhancement on co-registered
preoperative MR scans, 2) intraoperative ALA-induced PpIX fluorescence and 3) gold-standard
histology obtained from biopsy sampling during the procedure.
Subjects will include those people with operable brain tumor with first-time presumed
pre-surgical diagnosis of high-grade glioma or low-grade glioma.
View more details from ClinicalTrials.gov.
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