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Norris Cotton Cancer Center
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Potential Side Effects of I-125 Prostate Seed Implants

Any medical treatment may cause side effects or put you at risk for a more serious and/or permanent complication.

You may experience a few, none, or (very rarely) all of these side effects. Most will disappear or lessen with time. Also, if other types of treatment are given in conjunction with radiation therapy, side effects may be more frequent and/or more severe than if radiation therapy alone had been given.

Probable side effects

  • Fatigue
  • Pelvic discomfort
  • Urinary frequency (feeling the need to urinate frequently Urinary urgency, or feeling the need to urinate right away)

Possible side effects

  • Burning during urination
  • Urinary retention (passing urine, but unable to fully empty the bladder)
  • Urinary obstruction (unable to pass urine)
  • Rectal bleeding
  • Sexual dysfunction
  • Urinary incontinence (unable to control bladder)
  • Bowel incontinence (unable to control bowels)
  • Diarrhea

Rare side effects

  • Rectal injury requiring surgery

If you have any questions, please call Radiation Oncology: (603) 650-6600

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