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Norris Cotton Cancer Center
In This Section

Office of Clinical Research Structure and Support

Clinical Cancer Review Committee (CCRC)

Provides required peer review of scientific merit prior to IRB review. Reviews clinical research protocols for treatment, prevention, control or intervention of cancer and protocol amendments

NCCC Data, Safety Monitoring, and Accrual Committee (DSMAC)

Provides required peer review of clinical research protocols for which a Dartmouth investigator is both investigator and sponsor of the protocol. Review toxicity patterns, data integrity, protocol adherence, and progress toward study objectives. Reviews study accrual.

Clinical Trials Investigational Order Set Committee (CTIOSC)

Provides required review of drug order sets for clinical trials prior to study activation

Cancer Clinical Research Quality Improvement Committee (QIC)

Focuses on continuous clinical research process improvement at the Norris Cotton Cancer Center. Analyzes trends in the quality of research by quarterly reviews of protocol deviation reports, local serious adverse event reports, ongoing corrective and preventative actions plans, reports from research ancillary support services, and reports from PIs, NPs, Clinical Research Coordinators, Research Nurses, Regulatory staff, and administrators.