Research

Idylla device

Rapid Genomic Profiling of Colon Cancers can Improve Therapy Selection for Patients

Multicenter study led by NCCC shows vastly improved turnaround time to get results from the lab to the oncologist using the newest technology in the cancer testing space.

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Jason Faris, MD

What Types of Early-phase Trials are Open Now at NCCC?

In this Q&A series, Jason Faris, MD details some exciting and innovating early-phase trials underway at the cancer center.

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colorectal polyp mapping

New AI Model Accurately Classifies Colorectal Polyps Using Slides from 24 Institutions

Dartmouth researchers have created an AI model to classify colorectal polyps on histology slides. Evaluation using 238 slides from 24 institutions across 13 US states finds that the model performs as well as practicing pathologists.

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Breast tumor cells

Discovering a Key to the Survival of Dormant Breast Cancer Cells

A common anti-diabetes drug being tested in many clinical trials as an anti-cancer agent activated fat metabolism that promoted the survival of dormant breast cancer cells, suggesting that the drug has context-dependent effects on cancer cells.

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Participants under the balloon arch at The Prouty

Where Do Prouty Donations Go? Spring, 2020

Programming machine learning for cervical cancer screening, aiding survival of cancer-fighting immune cells, and measuring clinician emotion during difficult conversations. These are just some of the new cancer research studies funded by The Prouty.

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Women in cancer screening line

Rural Hondurans Embrace Cancer Screening Opportunities

An internationally collaborative group of Dartmouth and Honduran researchers and oncologists found a high level of compliance with referral to clinical follow-up among rural Honduran women and men attending cancer screening events.

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Jason Faris, MD

What Are Early-Phase Clinical Trials?

In this Q&A series, Jason Faris, MD, director of the Early-Phase Trials Program at Norris Cotton Cancer Center explains what early-phase clinical trials are and why they are so important to the advancement of cancer care.

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Image of the Extracelluar PtG4

Researchers Capture First Images of Oxygen in Cancer Tumors During Radiation Therapy

Using specialty cameras and an oxygen probe drug injection, researchers at Dartmouth’s Norris Cotton Cancer Center can now image oxygen from within cancer tumors during radiation while the probe is excited by Cherenkov light, a byproduct of radiation.

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Randolphe Noelle, PhD, in lab

Researchers Investigate Molecule, VISTA

A research team led by Dartmouth’s Norris Cotton Cancer Center learns how a certain immune checkpoint inhibitor molecule acts like “brakes,” quieting the immune system from responding to cancer.

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Diagram of mechanism

New Mechanism May Safely Prevent and Reverse Obesity

Researchers at Dartmouth’s Norris Cotton Cancer Center observed that blocking a cellular receptor not only prevented but reversed obesity, with no ill side effects, in mice.

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