Gastrointestinal Stromal Tumor (GIST)

What is a GIST?

A GIST is a gastrointestinal stromal tumor. A GIST is a rare tumor that starts in the wall of the gastrointestinal (GI) tract (or digestive tract).

Although a GIST can occur anywhere in the digestive tract, they are most often found in the stomach. These tumors can start in the part of the nervous system that regulates body functions, such as digestion.

More than half of GISTs start in the stomach. Most others start in the small intestine, but GISTs can arise anywhere along the GI tract. Some GISTs are more likely to spread to other parts of the body than others.

We look at factors that are unique to you, such as:

  • The size of the tumor
  • The location of the tumor
  • How fast the tumor cells are dividing

More information about GIST (American Cancer Society)

GIST tests and treatments

Depending on your specific condition, you may receive one or more of the following GIST tests and treatments.

GIST tests

  • Imaging (CT scan)
  • Endoscopy
  • Possible needle biopsy
  • Physical exam

GIST treatments

  • Oral targeted therapies
  • Radiation
  • Surgery

Dartmouth Cancer Center multidisciplinary team approach to treating GISTs

Our full multidisciplinary team of care providers works with you to:

  • Review your GIST diagnostic tests
  • Identify the best GIST treatment, particular to you
  • Help you understand your GIST diagnosis and what to expect with any treatment

Contact us at one of our locations near you.