Expert Research Committees

Our staff assists researchers in carrying out cancer-related clinical trials. This involves reviewing and approving trial protocols, conducting data and safety reviews and continuous research quality improvement. 

Clinical Cancer Review Committee (CCRC) 

The CCRC provides the required peer review of scientific merit prior to IRB review. Reviews clinical research protocols for treatment, prevention, and control; and approves protocol amendments.

Email Dr. Kris S. Williams at with any questions about this committee and review. 

Data Safety Monitoring and Accrual Committee (DSMAC) 

The DSMAC conducts data and safety reviews of clinical research protocols for which a Dartmouth investigator is both investigator and sponsor of the protocol; and reviews toxicity patterns, data integrity, protocol adherence, and progress toward study objectives, including study accrual rates.

Email Dr. Kris S. Williams at with any questions about this committee and review.

Clinical Trials Investigational Order Set Committee (CTIOSC)

The CTIOSC provides a required review of drug order sets for clinical trials prior to study activation.

Email Douglas D. Parr at with any questions about this committee. 

Cancer Clinical Research Quality Improvement Committee (QIC)

The QIC focuses on continuous clinical research process improvement at the Dartmouth Cancer Center. They analyze trends in the quality of research by quarterly reviews of protocol deviation reports, local serious adverse event reports, ongoing corrective and preventative actions plans, reports from research ancillary support services, and reports from principal investigators, NPs, clinical research coordinators, research nurses, regulatory staff, and administrators.

Email Erin E. Lynch at with any questions.