The Genomics and Molecular Biology Shared Resources (GMBSR) is a highly collaborative resource and provides Dartmouth researchers with access to cutting-edge instrumentation and expertise, with rapid turnaround times and cost-effective solutions.
Technologies are available for DNA and RNA sequencing, as well as DNA methylation analysis using both whole-genome and targeted approaches. A comprehensive suite of services supports single-cell and spatial omics applications, including tissue processing, QC, library preparation and sequencing, as well as tissue staining and imaging in collaboration with the Pathology and Microscopy Shared Resources.
GMBSR also provides NanoString nCounter gene expression profiling and long-read plasmid and amplicon sequencing on Oxford Nanopore. Plasmid/amplicon sequencing runs twice weekly (Monday and Thursday) and delivers both the raw reads and fully assembled, annotated constructs. This service replaces Sanger sequencing, which has been discontinued. Integration with the Genomic Data Science Core provides dedicated analysis solutions for all GMBSR workflows.
For detailed service descriptions, sample submission guidelines and instrumentation, visit the GMBSR website. To estimate the cost of a project, use the Genomics Cost Calculator. Orders are placed through RaDar.