Pathology Shared Resource

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Pathology Shared Resource

Borwell Building 510W, 546W, 581W, and WTRB 4th floor
Norris Cotton Cancer Center
One Medical Center Drive
Lebanon, NH 03756
(603) 650-6821

Pricing information and sample submission

Our mission is to facilitate project planning, clinical validation and implementation of novel translational technology and research in the fields of molecular diagnostics, molecular therapeutics, pharmacogenomics, quantitative morphologic image analysis and immunohistochemistry (IHC) in a CLIA-certified, CAP-accredited laboratory ensuring optimal clinical quality assurance. This past year, the PSR expanded its physical footprint by moving all of the histology and cell therapy services to the 5th floor of the Borwell Building and expanding the genomics services on the 4th floor of the WTRB.

Leadership

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Gregory J. Tsongalis, PhD, HCLD

Gregory J. Tsongalis, PhD, HCLD
Director
Professor of Pathology
Director, Clinical Genomics and Advanced Technology (CGAT)
Gregory.J.Tsongalis@Dartmouth.edu
Board certified in Molecular Diagnostics

Responsible for:

  • Experimental planning and implementation support
  • Daily operations
  • Instrument acquisition
  • External clinical trials, evaluations and funding resources
  • Total quality management (PT testing, accreditation/inspection)
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Wendy A. Wells, MD, MSc

Wendy A. Wells, MD, MSc
Faculty Co-Director
Professor and Chair, Department of Pathology and Laboratory Medicine (CAP-accredited and CLIA-certified), DHMC-Director
Wendy.A.Wells@Hitchcock.org
Board certified in surgical and cyto-pathology with specialist expertise in breast cancer.

Responsible for oversight and quality control management of:

  • Histology, including special stains
  • Immunohistochemistry
  • Tissue Microarray (TMA) creation
  • Quantitative image processing and analysis
  • Tissue procurement, complex protocols

Staff

  • Amber Erskine – Program coordinator
  • Rebecca O’Meara – Histotechnologist
  • David Beck – Histotechnologist
  • Scott Palisoul – Histotechnologist
  • Torrey Gallagher – Institutional Biorepository Coordinator

Services

Animal studies

  • Tissue processing/block creation
    • Histology
    • Unstained section
    • Hematoxylin and Eosin (H&E)
  • Stained section
    • Special stains

Human studies

  • Tissue processing/block creation:
    • Histology
    • Unstained section
    • Hematoxylin and Eosin (H&E)
  • Stained section
    • Special stains
  • Tissue Procurement
    • Fresh Tissue, customized
    • (protocol-based)
    • Tissue Bank Retrieval (fresh frozen)
  • Immunohistochemistry
    • Routine Antibodies
    • Testing of Antibodies
    • (protocol-based)
    • Antibody purchase
  • Quantitative image processing and analysis (protocol-based)
  • Tissue Microarrays creation and use (protocol-based)
    • Standard
    • Customized
  • Molecular pathology: molecular diagnostic testing development and validation, SNP genotyping, gene expression, miRNA expression (protocol-based)
    • Next Generation sequencing
    • Clinical Pathology Laboratory testing (protocol-based)
    • Apheresis Collection (protocol-based)

Clinical trial studies

  • Tissue processing (protocol-based)
  • Histology (protocol-based)

Administrative requests (handling)

  • Off-site block and/or slide retrieval
  • LIS review (protocol-based)
  • CIS review (protocol-based)

Drop off

The drop-off site is available 24/7 in the histology lab in the Borwell Building on Level 4, as long as refrigeration is not needed. If the sample needs to be refrigerated, please contact the program administrator and set up a time, during business hours, to deliver samples.

Sample requirements

Samples for routine histology must be in cassettes and placed in a container with 10% formalin, Samples requiring alternative handling must be discussed/scheduled with the program administrator.

Data interpretation help if applicable

The PTRP Core personnel are available to assist with data review. Please contact the program administrator to schedule a meeting date/time.