Street Address:
Room 243
Remsen Building
Geisel School of Medicine at Dartmouth
Hanover, NH 03755
(603) 650-6546
Email: mbcore@dartmouth.edu
Dartmouth Molecular Biology Shared Resource website
Pricing information and sample submission
This core facility provides molecular biology products, services, and support to help investigators solve their basic, translational, and clinical research problems. Our services include DNA fragment analysis, qPCR, Sanger sequencing and NanoString Technology. It is our goal to offer the highest quality products and services possible in the most cost-effective manner.
Shipping Address:
Vail Receiving
Room 243
North College Street
Hanover, NH 03755
Leadership
Yolanda Sanchez, PhD
Faculty Advisor
Associate Professor, Dept. of Pharmacology and Toxicology
Yolanda.Sanchez@Dartmouth.edu
Dr. Sanchez's laboratory focuses on checkpoint signaling events triggered by DNA damage or replication interference.
Christian Lytle
Lead Tech/Manager
American Society for Clinical Pathology
Board of Certification CG(ASCP)CM
The Association of Biomolecular Resource Facilities (ABRF)
North East Regional Life Science Core Directors (NERLSCD)
Christian.Lytle@Dartmouth.edu
Sharon Tyndall
Tech
Sharon.Tyndall@Dartmouth.edu
Molecular Biology services
- NanoString Technologies
- Sample preparation for Sanger DNA sequencing
- Sanger DNA sequencing
- DNA fragment analysis
- Data review, troubleshooting and analysis resources
Supported applications
- AFLP
- BAC Fingerprinting
- Methylation
- LOH (loss of heterozygosity)
- Digital Genomics
- Pathway-based Translational Research
- Gene Expression
- miRNA
- CNV
Sequencing Analysis software - Automated basecalling, and assigns quality values. Allows the option to visualize, edit, print and re-basecall sequencing data using the KB basecaller. SeqScape software- Offers the most complete solution for variant detection projects. The software reads Genbank files to create a reference sequence and annotate sequence features such as protein coding sequence, introns, and exons. In addition, data from dbSNP can be automatically imported to provide accurate nucleotide variants information.
GeneMapper software - Enables configurable, automated allele calling, a valuable asset for high-throughput genotyping. The software can process over 100,000 genotypes per hour, and significantly reduce the time and effort in the genotyping process.